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Merck

5133

Sigma-Aldrich

Bovine Collagen Type I & III

from bovine hide, liquid, 10 mg/mL, suitable for cell culture, used for 3D hydrogel formation, FlexiCol®

别名:

Sepharose 4B

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.75

product name

FibriCol®, Collagen solution from Bovine hide, 97% Type I with the remainder of Type III collagen, suitable for cell culture

生物源

(Collagen solution from Bovine hide)

品質等級

無菌

sterile-filtered

化驗

>99% (SDS-PAGE Electrophoresis – Silver Stain, SDS-PAGE)

形狀

solution

包裝

pkg of 20 mL

技術

cell culture | mammalian: suitable

溶解度

water: miscible

運輸包裝

wet ice

儲存溫度

2-8°C

一般說明

FibriCol® collagen is approximately 97% Type I collagen with the remainder being comprised of Type III collagen. It contains a high monomer content as measured by gel permeation chromatography.

It is ideal for applications where high concentrations of collagen are needed. FibriCol® collagen is provided in a 20 mL volume and is contained in user-friendly packaging for use and storage. FibriCol® is sterile filtered and is supplied as a ready to use solution.

應用

FibriCol® has been used:

  • in the preparation of liposome-loaded co-gels to treat methicillin-resistant Staphylococcus aureus (MRSA) infections in vitro and in vivo
  • in the preparation of gelatin-methacrylate (gelMA)-collagen gels to study the effects of stiffness and fiber density on cellular behavior in breast cancer cell lines
  • in the preparation of collagen hydrogels to study its effects on macrophage response in partial thickness abdominal wall defect rat models

法律資訊

FibriCol is a registered trademark of Advanced BioMatrix, Inc.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Host macrophage response to injectable hydrogels derived from ECM and ?-helical peptides
Nazia M, et al.
Acta Biomaterialia, 111, 141-152 (2020)
Anthony J Berger et al.
Biomaterials, 141, 125-135 (2017-07-07)
The extracellular microenvironment provides critical cues that guide tissue development, homeostasis, and pathology. Deciphering the individual roles of these cues in tissue function necessitates the development of physically tunable culture platforms, but current approaches to create such materials have produced
Raj Kumar Thapa et al.
Acta biomaterialia, 103, 115-128 (2019-12-18)
Wound infections are a significant clinical problem affecting millions of people worldwide. Topically applied antibacterial formulations with longer residence time and controlled antimicrobial release would offer significant benefits for improved prevention and treatment of infected wounds. In this study, we

商品

The extracellular matrix (ECM) and its attachment factor components are discussed in this article in relation to their function in structural biology and their availability for in vitro applications.

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