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Merck

27042

Sigma-Aldrich

硫酸软骨素 4-硫酸盐 钠盐 来源于牛气管

mixture of isomers, main component: chondroitin 4-sulfate

别名:

CSA, 硫酸软骨素A 钠盐

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

bovine trachea

品質等級

形狀

powder

光學活性

[α]20/D −25±5°, c = 1% in H2O

雜質

≤10% water

溶解度

H2O: 0.1 g/mL, clear to slightly turbid, colorless to light yellow

儲存溫度

2-8°C

SMILES 字串

CC1=C(CCN2CCC(\CC2)=C(/c3ccccc3)c4ccc(F)cc4)C(=O)N5C=CSC5=N1

應用

软骨素是一种氨基葡聚糖 (GAG),是 N-乙酰半乳糖胺 (GalNAc) 和葡萄糖醛酸 (GlcA) 交替单位的多糖链,可在 GalNAc 和 GlcA 单位上发生硫酸化。软骨素及其硫酸盐经常附着在蛋白质上形成蛋白聚糖。

其他說明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。
销售限制可能适用

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Tomomi Izumikawa et al.
Biochimica et biophysica acta, 1830(10), 4806-4812 (2013-07-03)
Previously, we identified two missense mutations in the chondroitin N-acetylgalactosaminyltransferase-1 gene in patients with neuropathy. These mutations are associated with a profound decrease in chondroitin N-acetylgalactosaminyltransferase-1 enzyme activity. Here, we describe a patient with neuropathy who is heterozygous for a
Gunnar Dick et al.
The Journal of biological chemistry, 288(38), 27384-27395 (2013-08-14)
Chondroitin sulfate (CS) and the CS-rich extracellular matrix structures called perineuronal nets (PNNs) restrict plasticity and regeneration in the CNS. Plasticity is enhanced by chondroitinase ABC treatment that removes CS from its core protein in the chondroitin sulfate proteoglycans or
Clare M Galtrey et al.
Brain research reviews, 54(1), 1-18 (2007-01-16)
Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan (GAG) chains. There is enormous structural diversity among CSPGs due to variation in the core protein, the number of GAG chains and the extent and position of sulfation. Most
Tadahisa Mikami et al.
Biochimica et biophysica acta, 1830(10), 4719-4733 (2013-06-19)
Chondroitin sulfate proteoglycans (CSPGs) are principal pericellular and extracellular components that form regulatory milieu involving numerous biological and pathophysiological phenomena. Diverse functions of CSPGs can be mainly attributed to structural variability of their polysaccharide moieties, chondroitin sulfate glycosaminoglycans (CS-GAG). Comprehensive
Hong-Peng Li et al.
Journal of neurotrauma, 30(5), 413-425 (2013-02-27)
Dermatan sulfate (DS) is synthesized from chondroitin sulfate (CS) by epimerization of glucuronic acid of CS to yield iduronic acid. In the present study, the role of CS and DS was examined in mice that received transection of nigrostriatal dopaminergic

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