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Merck

21932

Sigma-Aldrich

5(6)-Carboxynaphthofluorescein

BioReagent, suitable for fluorescence, ≥90% (HPLC)

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About This Item

经验公式(希尔记法):
C29H16O7
分子量:
476.43
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.32

產品線

BioReagent

化驗

≥90% (HPLC)

形狀

solid

pKa 

7.6

螢光

λex 512 nm; λem 567 nm (acid/neutral)
λex 598 nm; λem 668 nm (basic)

適合性

suitable for fluorescence

SMILES 字串

OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc5cc(O)ccc5c4Oc6c3ccc7cc(O)ccc67.OC(=O)c8ccc9C(=O)OC%10(c%11ccc%12cc(O)ccc%12c%11Oc%13c%10ccc%14cc(O)ccc%13%14)c9c8

InChI

1S/2C29H16O7/c30-17-4-6-19-14(11-17)1-9-23-25(19)35-26-20-7-5-18(31)12-15(20)2-10-24(26)29(23)22-8-3-16(27(32)33)13-21(22)28(34)36-29;30-17-4-7-19-14(11-17)2-9-22-25(19)35-26-20-8-5-18(31)12-15(20)3-10-23(26)29(22)24-13-16(27(32)33)1-6-21(24)28(34)36-29/h2*1-13,30-31H,(H,32,33)

InChI 密鑰

ANUHNEJUELPITC-UHFFFAOYSA-N

應用

5(6)-Carboxynaphthofluorescein (CNF) may be used as an intravesicular pH-sensitive probe for the detection of activity, selectivity and cooperativity of ion channels such as gramicidin A.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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D A Jankowska et al.
Biosensors & bioelectronics, 87, 312-319 (2016-08-31)
Aging population and longer life expectancy are the main reasons for an increasing number of patients with wound problems. Although the interest in wound care increases continuously, wound management still remains a challenge mainly due to the higher occurrence of
A Song et al.
Analytical chemistry, 69(5), 863-867 (1997-03-01)
A fast and durable ratiometric pH microoptode that is highly accurate, precise, sensitive, reversible, and reproducible over the physiological ranges of pH, ionic strength, and temperature has been developed. The sensing site consists of 5 (and 6)-carboxynaphthofluorescein (CNF) entrapped in
M Ramanathan et al.
Biosensors & bioelectronics, 22(12), 3001-3007 (2007-02-03)
The aim of the present work is to develop an evanescence wave array biosensor exploiting the "kinetic" approach of enzymatic reaction and further detection of the reaction products via pH sensitive fluorophore reporter. To demonstrate the feasibility of this approach
Shannon G Klein et al.
Global change biology, 23(9), 3690-3703 (2017-04-09)
Anthropogenic nutrient inputs enhance microbial respiration within many coastal ecosystems, driving concurrent hypoxia and acidification. During photosynthesis, Symbiodinium spp., the microalgal endosymbionts of cnidarians and other marine phyla, produce O
Giorgia Giovannini et al.
Nanomaterials (Basel, Switzerland), 11(1) (2021-01-21)
The development of hybrid materials with unique optical properties has been a challenge for the creation of high-performance composites. The improved photophysical and photochemical properties observed when fluorophores interact with clay minerals, as well as the accessibility and easy handling

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