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Merck
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主要文件

Y0000394

地匹福林

European Pharmacopoeia (EP) Reference Standard

别名:

Dipivefrin hydrochloride

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About This Item

经验公式(希尔记法):
C19H29NO5 · HCl
CAS号:
分子量:
387.90
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

dipivefrine

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

[Cl-].[N+H2](CC(O)c1cc(c(cc1)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)C

InChI

1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

InChI key

VKFAUCPBMAGVRG-UHFFFAOYSA-N

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Dipivefrine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Contact dermatitis from dipivefrine with possible cross-reaction to epinephrine.
A Parra et al.
Contact dermatitis, 39(6), 325-326 (1999-01-05)
M R Holdiness
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 12(4), 217-219 (2001-12-26)
A review of the literature has identified 10 agents causing contact dermatitis among topically administered drugs for glaucoma. These agents include beta-blockers (timolol, befunolol, betaxolol, levobunolol, carteolol, metipranolol), a carbonic anhydrase inhibitor (dorzolamide), a parasympathomimetic (pilocarpine), and sympathomimetics (dipivefrin, apraclonidine).
Show-Jen Hong et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 19(3), 205-215 (2003-06-28)
Over releasing of glutamate and cellular calcium influx always results in neuronal death. In the present study, we investigated various commercial antiglaucoma drugs including timolol (0.58 microM to 58 microM), betaxolol (1.62 microM to 162 microM), carteolol (6.8 microM to
A O D'Ostroph et al.
Ophthalmic plastic and reconstructive surgery, 17(5), 328-331 (2001-10-20)
To report patients who presented to the oculoplastics department for repair of cicatrical entropion after topical use of dipivefrin. To discuss the possible mechanisms of action and highlight the potential detrimental effects of dipivefrin on palpebral conjunctiva. Retrospective consecutive noncomparative
D F Edgar et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 237(2), 117-124 (1999-02-13)
A study was carried out to ascertain, in ophthalmologically normal subjects, the short-term effects of dipivefrin hydrochloride 0.1% on visual performance and make comparisons with pilocarpine. Twelve normal volunteers aged 20-26 years attended on three occasions. One eye, randomly selected

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