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等級
certified reference material
pharmaceutical secondary standard
品質等級
agency
traceable to BP 421
traceable to Ph. Eur. P3400000
traceable to USP 1570009
API 家族
promethazine
CofA
current certificate can be downloaded
包裝
pkg of 1 g
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-8°C
SMILES 字串
Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C
InChI
1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI 密鑰
XXPDBLUZJRXNNZ-UHFFFAOYSA-N
基因資訊
human ... HRH1(3269)
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一般說明
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Promethazine hydrochloride belongs to the group of phenothiazine derivatives. It is commonly used as an antihistaminic for most prominently enhancing the anesthetic, sedative and analgesic effect of other drugs. It also shows antipyretic and antiemetic properties, when used in combination with paracetamol. It is also used to provide symptomatic relief of hypersensitivity reactions.
應用
Promethazine hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectroanalytical technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
分析報告
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
其他說明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
腳註
To see an example of a Certificate of Analysis for this material enter LRAA3015 in the slot below. This is an example certificate only and may not be the lot that you receive.
相關產品
产品编号
说明
价格
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Flow injection spectro-electroanalytical method for the determination of promethazine hydrochloride in pharmaceutical preparations.
Daniel D, et al.
Analytica Chimica Acta, 494(1-2), 215-224 (2003)
Mario Schietroma et al.
Journal of the American College of Surgeons, 220(5), 921-933 (2015-04-05)
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. An independent statistical analysis based on the summary data tables and statistical results reported in the
Cheryl C Y Loh et al.
PloS one, 9(10), e110800-e110800 (2014-10-25)
Chloroquine was a cheap, extremely effective drug against Plasmodium falciparum until resistance arose. One approach to reversing resistance is the inhibition of chloroquine efflux from its site of action, the parasite digestive vacuole. Chloroquine accumulation studies have traditionally relied on
Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human
Jung Yeon Kim et al.
Biomedical chromatography : BMC, 29(3), 465-474 (2014-08-01)
The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The limits of detection and quantitation of the method ranged from 1.5 to 2.5
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