PHR1179

氯噻嗪

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 经验公式（希尔记法）: C₇H₆ClN₃O₄S₂
• CAS号: 58-94-6
• 分子量: 295.72
• EC號碼: 200-404-9
• MDL號碼: MFCD00058576
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823191
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 76; traceable to Ph. Eur. C1700000; traceable to USP 1121005
• API 家族: chlorothiazide
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: O=S(C1=C2C=C(Cl)C(S(N)(=O)=O)=C1)(NC=N2)=O
• InChI: 1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13)
• InChI 密鑰: JBMKAUGHUNFTOL-UHFFFAOYSA-N
• 基因資訊: human ... SLC12A3(6559)

说明

一般說明

Chlorothiazide belongs to the class of thiazide diuretic drugs. It is used for the management of postparturient udder edema in cattle. Its mode of action involves the inhibition of chloride reabsorption in the proximal portion of distal tubule.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Chlorothiazide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

One of the first in the thiazide class of diuretics.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA8998 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H317,H334
• 防範說明: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• 危險分類: Resp. Sens. 1 - Skin Sens. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable