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Merck

PHR1016

Supelco

马来酸氯苯那敏

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(±)-氯苯那敏 马来酸盐

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About This Item

经验公式(希尔记法):
C16H19ClN2 · C4H4O4
CAS号:
分子量:
390.86
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to BP 81
traceable to Ph. Eur. C1800000
traceable to USP 1123000

API 家族

chlorpheniramine

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

130-135 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-30°C

SMILES 字串

CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI 密鑰

DBAKFASWICGISY-BTJKTKAUSA-N

基因資訊

human ... HRH1(3269)

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一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Chlorpheniramine Maleate is an H1-receptor antagonist drug grouped under the class of antihistaminic compounds.

應用

Chlorpheniramine Maleate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

H 1 组胺受体拮抗剂。

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC0771 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相關產品

产品编号
说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Normal-phase LC method for simultaneous analysis of pseudophedrine hydrochloride, dextromethorphan hydrobromide, chlorpheniramine maleate, and paracetamol in tablet formulations
Al-Rimawi F
Saudi Pharmaceutical Journal : SPJ : The Official Publication of the Saudi Pharmaceutical Society, 18(2), 103-106 (2010)
Poly (ethyleneglycol) column for the determination of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations
Garcia A, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 785(2), 237-243 (2003)
New approaches with two cyano columns to the separation of acetaminophen, phenylephrine, chlorpheniramine and related compounds
Olmo B, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 817(2), 159-165 (2005)
CE versus HPLC for the dissolution test in a pharmaceutical formulation containing acetaminophen, phenylephrine and chlorpheniramine
Marin A and Barbas C
Journal of Pharmaceutical and Biomedical Analysis, 35(4), 769-777 (2004)
Validation of a HPLC quantification of acetaminophen, phenylephrine and chlorpheniramine in pharmaceutical formulations: capsules and sachets.
Marin A, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(4), 701-714 (2002)

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