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Merck

P3800000

Proxyphylline

European Pharmacopoeia (EP) Reference Standard

别名:

7-(β-Hydroxypropyl)theophylline, (1,3-Dimethyl-7-[2-hydroxypropyl]-2,6-dioxopurine), Proxyphylline

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About This Item

经验公式(希尔记法):
C10H14N4O3
CAS号:
分子量:
238.24
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

proxyphylline

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC(O)Cn1cnc2N(C)C(=O)N(C)C(=O)c12

InChI

1S/C10H14N4O3/c1-6(15)4-14-5-11-8-7(14)9(16)13(3)10(17)12(8)2/h5-6,15H,4H2,1-3H3

InChI key

KYHQZNGJUGFTGR-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Proxyphylline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D Agbaba et al.
Biomedical chromatography : BMC, 6(3), 141-142 (1992-05-01)
The content and dissolution rate of theophylline, diprophylline and proxyphylline from a sustained release formulation were determined by UV in situ densitometry. After separation the chromatographic zones corresponding to the spots of theophylline, diprophylline and proxyphylline on the high performance
A R Khare et al.
Journal of biomaterials science. Polymer edition, 4(3), 275-289 (1993-01-01)
Controlled release systems of theophylline, proxyphylline and oxprenolol.HCl exhibiting modulated drug delivery were prepared by using pH-sensitive anionic copolymers of 2-hydroxyethyl methacrylate with acrylic acid or methacrylic acid. Drug release studies were carried out in simulated biological fluids. The initial
H Magnussen et al.
Deutsche medizinische Wochenschrift (1946), 111(1), 15-19 (1986-01-03)
In study I, carried out on 9 asthmatics to investigate whether the bronchodilator and protective effect of intravenous theophylline, dissolved in ethylene diamine (T.E.) or proxyphylline and diprophylline (T.P.D.), showed different dose-effect relationships, 100 mg theophylline with T.E., T.P.D. or
Linfeng Wu et al.
International journal of pharmaceutics, 349(1-2), 1-10 (2007-09-11)
Delayed release systems find applications in chronotherapeutics and colon-specific delivery. They have also been considered suitable carriers for the oral delivery of peptides and proteins. In prior work, our research group has reported surface crosslinking as an effective technique to
H Magnussen et al.
Chest, 90(5), 722-725 (1986-11-01)
To compare the acute bronchodilator effect of increasing doses of intravenous theophylline and inhaled beta adrenergic agonists, we administered intravenous theophylline dissolved in ethylenediamine or proxyphylline and diprophylline or placebo in a double blind fashion to nine asthmatics on three

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