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Merck

C0470000

羧甲司坦

European Pharmacopoeia (EP) Reference Standard

别名:

S-羧甲基-L-半胱氨酸, 3-羧甲基硫代-L-丙氨酸

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About This Item

经验公式(希尔记法):
C5H9NO4S
CAS号:
分子量:
179.19
Beilstein:
1725012
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

carbocisteine

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

N[C@@H](CSCC(O)=O)C(O)=O

InChI

1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

InChI 密鑰

GBFLZEXEOZUWRN-VKHMYHEASA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Carbocisteine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yuji Ishibashi et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(6), 699-704 (2012-06-13)
Human bronchial mucins, such as MUC5AC, have traditionally been defined as a family of high-molecular weight glycoproteins. Changes in the contents of sugar chains on MUC5AC are among the fundamental features in inflammatory respiratory disease. The changes have been shown
Steve C Mitchell et al.
Drug metabolism reviews, 44(2), 129-147 (2012-04-14)
S-carboxymethyl-L-cysteine, the side-chain carboxymethyl derivative of the sulfur-containing amino acid, cysteine, has been known and available for almost 80 years. During this time, it has been put to a variety of uses, but it is within the field of respiratory
Pauline Mallet et al.
PloS one, 6(7), e22792-e22792 (2011-08-06)
To report pediatric cases of paradoxical respiratory adverse drug reactions (ADRs) after exposure to oral mucolytic drugs (carbocysteine, acetylcysteine) that led to the withdrawal of licenses for these drugs for infants in France and then Italy. The study followed the
Drug fever due to S-carboxymethyl-L-cystein: demonstration of a causative agent with patch tests.
Mayumi Hatakeyama et al.
The Journal of dermatology, 39(6), 555-556 (2011-09-29)
Qing Zhai et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 67(3-4), 215-221 (2012-05-26)
Hepatic injury induced by oxaliplatin has been reported. Even though agents are available that reduce oxaliplatin-induced hepatocyte toxicity, their mode of action has remained obscure. In the present study, hepatic L02 cells were incubated with different combinations of oxaliplatin and

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