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Merck
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文件

B3022

Supelco

二丙酸倍氯米松

analytical standard, for drug analysis

别名:

9-氯-11β,17,21-三羟基-16β-甲基孕甾-1,4-二烯-3,20-二酮-17,21-二丙酸酯

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About This Item

经验公式（希尔记法）:
C28H37ClO7
CAS号:
5534-09-8
分子量:
521.04
EC號碼:
226-886-0
MDL號碼:
MFCD00135613
分類程式碼代碼:
41116107
PubChem物質ID:
329773210
NACRES:
NA.24

等級

analytical standard, for drug analysis

品質等級

200

化驗

≥99%

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
veterinary

格式

neat

儲存溫度

2-8°C

SMILES 字串

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C

InChI

1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1

InChI 密鑰

KUVIULQEHSCUHY-XYWKZLDCSA-N

基因資訊

human ... NR3C1(2908)

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一般說明

Beclomethasone dipropionate belongs to the chemical class of chlorinated glucocorticoid diesters, well known for its use in the treatment of asthma due to its anti-inflammatory properties.

應用

Beclomethasone dipropionate analytical standard can be used as follows:
  • Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method, combined with UV detection to determine beclomethasone dipropionate in nanocapsule suspensions
  • Simultaneous determination of beclomethasone dipropionate and ketoconazole in their bulk and combined cream formulations using UV-spectrophotometry and RP-HPLC based methods
  • Estimation of beclomethasone dipropionate and formoterol fumarate in their combined dosage forms by stability indicating RP-HPLC method coupled with UV detection
  • Combined analysis of beclomethasone dipropionate and formoterol fumarate dihydrate using two UV-spectrometric and one RP-HPLC based methods in bulk and their pharmaceutical dosage forms
  • Multi-residue analysis of 21 glucocorticoids in environmental samples by ultra-high performance liquid chromatography (UHPLC) and mass spectrometry (MS)

其他說明

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Health hazard
GHS08

訊號詞

Warning

危險聲明

H361fd,H373

危險分類

Repr. 2 - STOT RE 2

標靶器官

Adrenal gland,Immune system,Bone

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
0000399934
0000399929
0000388006
0000364585
0000364585

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Quick Review of Pharmacology null
Tiago Nunes et al.
Journal of Crohn's & colitis, 7(3), 183-191 (2012-07-13)
IBD is a chronic and relapsing inflammatory disorder of the gut that demands long-lasting treatment targeting both flare-up periods and maintenance of remission. Oral systemic steroids have been used to induce remission in patients with active IBD for over 50
Jessica K Roberts et al.
The Journal of pharmacology and experimental therapeutics, 345(2), 308-316 (2013-03-21)
Inhaled glucocorticoids, such as beclomethasone dipropionate (BDP), are the mainstay treatment of asthma. However, ≈ 30% of patients exhibit little to no benefit from treatment. It has been postulated that glucocorticoid resistance, or insensitivity, is attributable to individual differences in
Kai-Michael Beeh et al.
The Journal of allergy and clinical immunology, 131(3), 866-874 (2013-02-07)
Allergen-specific TH2 responses contribute to the development of allergic asthma. Their increase may be due to a reduced early exposure to environmental pathogens, which induces a TH1 response, and thereby suppresses the allergic TH2 response. QbG10 (bacteriophage Qbeta-derived virus-like particle
Eli O Meltzer et al.
Allergy and asthma proceedings, 33(3), 249-257 (2012-06-28)
Intranasal corticosteroids are recommended as first-line therapy for the treatment of the symptoms of persistent allergic rhinitis (AR). Since the phase-out of chlorofluorocarbon nasal aerosols, intranasal corticosteroids have been available only as aqueous nasal sprays. This study was designed to
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