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Merck

94348

Supelco

N-(3-Phenylpropionyl)glycine

analytical standard

别名:

2-[(3-Phenylpropionyl)amino]acetic acid, 3-Phenylpropionyl glycine, N-(1-Oxo-3-phenylpropyl)glycine, N-(3-Phenylpropanoyl)glycine

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About This Item

经验公式(希尔记法):
C11H13NO3
CAS号:
分子量:
207.23
Beilstein:
2976435
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:

等級

analytical standard

品質等級

化驗

≥98.0% (HPLC)

儲存期限

limited shelf life, expiry date on the label

應用

clinical testing

格式

neat

儲存溫度

2-8°C

InChI

1S/C11H13NO3/c13-10(12-8-11(14)15)7-6-9-4-2-1-3-5-9/h1-5H,6-8H2,(H,12,13)(H,14,15)

InChI 密鑰

YEIQSAXUPKPPBN-UHFFFAOYSA-N

生化/生理作用

Phenylpropionylglycine is an acylglycine. Acylglycines are normally minor metabolites of fatty acids. However, the excretion of certain acylglycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine ↔ CoA + N-acylglycine. The detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid can be used to diagnose deficiency of medium-chain acyl-CoA dehydrogenase, a frequent and treatable metabolic defect.

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象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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B Flath et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(1), 227-232 (1997-06-20)
Deficiency of medium-chain acyl-CoA dehydrogenase is a frequent and treatable metabolic defect, which can be diagnosed by detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid. We studied the determination of phenylpropionylglycine in urine by isocratic ion-exclusion

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