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Merck

81275

Sigma-Aldrich

聚(乙二醇)

tested according to Ph. Eur., 20,000

别名:

Macrogol 20,000, 聚氧乙烯, PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.21

agency

tested according to Ph. Eur.

品質等級

形狀

flakes

分子量

16000-24000

應用

pharmaceutical (small molecule)

SMILES 字串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般說明

聚乙二醇(PEG)是多功效的非离子型聚合物,低毒性、疏水性和半晶体结构令其广泛用于工业和药物领域。PEG由重复的CH2-CH2O单元组成,即使在高温条件下也能溶于单体和水相,在各种研究中发挥重要作用。

應用


  • Novel fibrous Ag(NP) decorated clay-polymer composite: Implications in water purification contaminated with predominant micro-pollutants and bacteria: This study demonstrates the use of poly(ethylene glycol) (PEG) for the creation of novel fibrous clay-polymer composites, enhancing the removal efficiency of micro-pollutants and bacteria in water treatment systems (Goswami et al., 2024).

  • Striving for Uniformity: A Review on Advances and Challenges To Achieve Uniform Polyethylene Glycol: This review addresses the advances in the uniform production of poly(ethylene glycol) (PEG), critical for its application in drug delivery and pharmaceutical formulations, discussing the material′s solubility, biocompatibility, and stabilization properties (Bento et al., 2024).

  • Assessing the structural stability and drug encapsulation efficiency of poly(ethylene glycol)-poly(L-lactic acid) nanoparticles loaded with atorvastatin calcium: The study evaluates the use of PEG in polymeric nanoparticles, focusing on optimizing drug encapsulation efficiency and stability, which is pivotal for effective drug delivery systems (Feng et al., 2024).

  • Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes: This research explores the role of PEG in designing responsive nanoscale materials aimed at targeting epigenetic enzymes, showcasing PEG′s versatility in enhancing pharmaceutical applications (Ray et al., 2024).

  • Membranes composed of poly(lactic acid)/poly(ethylene glycol) and Ora-pro-nóbis (Pereskia aculeata Miller) extract for dressing applications: This article highlights the application of PEG in developing biocompatible and efficient wound dressing materials, combining poly(lactic acid) and natural extracts to enhance healing processes (Mendes et al., 2024).


生化/生理作用

聚乙二醇(PEG或macrogol)广泛用作化妆品和药品中的添加剂。添加这种亲水性聚合物后,可体外阻断和逆转某些表面活性剂的失活。PEG及其衍生物或改性物可用作乳液聚合的大分子引发剂、稳定剂、分散剂。

特點和優勢

  • 环境优化型
  • 生物相容性
  • 独特的溶剂

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

281.5 °F - closed cup

閃點(°C)

138.6 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Polymer nanocomposites for biomedical applications
Rahmani S, et al.
Journal of Separation Science, 175-215 (2022)
Yiming Shi et al.
Langmuir : the ACS journal of surfaces and colloids, 29(9), 3024-3033 (2013-02-26)
Through zeta potential and surface tension measurements and a series of polymerization experiments, the role of poly(ethylene glycol) (PEG) in the process of surfactant-free polymerization of styrene (St)/methyl methacrylate (MMA) has been investigated experimentally. Nanoscale and stable copolymer particles were
K W Lu et al.
American journal of respiratory and critical care medicine, 164(8 Pt 1), 1531-1536 (2001-11-13)
Addition of nonionic polymers such as polyethylene glycol (PEG) and dextran ameliorates inactivation of Survanta by a variety of substances in vitro. Addition of polymers to Survanta also improves pulmonary function when used to treat rats with lung injury caused
Katharina Wylon et al.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 12, 67-67 (2016-12-22)
Polyethylene glycols (PEGs) or macrogols are polyether compounds and are widely used as additives in pharmaceuticals, cosmetics, and food. We report on a Caucasian patient experiencing recurrent severe allergic reactions to several drugs. An extensive diagnostic workup including skin prick
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced

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