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Merck

74711

Sigma-Aldrich

赭曲霉毒素A

purum, ≥98.0% (TLC), from Aspergillus ochraceus

别名:

N-[(3R)-(5-氯-8-羟基-3-甲基-1-氧代-7-异苯并二氢吡喃基)羰基]-L-苯丙氨酸

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About This Item

经验公式(希尔记法):
C20H18ClNO6
CAS号:
分子量:
403.81
Beilstein:
1301486
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

生物源

Aspergillus ochraceus

等級

purum

化驗

≥98.0% (TLC)

形狀

powder

作用方式

enzyme | inhibits
protein synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

C[C@@H]1Cc2c(Cl)cc(c(O)c2C(=O)O1)C(=O)N[C@@H](Cc3ccccc3)C(O)=O

InChI

1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1

InChI 密鑰

RWQKHEORZBHNRI-BMIGLBTASA-N

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其他說明

Inhibitor of mitochondrial transport systems; Mode of action.

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R. Roschenthaler et al.
J. Toxicol.-Toxin Reviews, 3, 53-53 (1984)
Ochratoxin A, an inhibitor of mitochondrial transport systems.
H Meisner et al.
Biochemistry, 13(14), 2795-2800 (1974-07-02)
Fiorenza Minervini et al.
Toxins, 5(1), 84-92 (2013-01-25)
Ochratoxin A (OTA) is a renal mycotoxin and transplacental genotoxic carcinogen. The aim of this study was to evaluate the natural occurrence of OTA in equine blood samples and its placental transfer. For the assessment of OTA levels, serum samples
Yan Wang et al.
Plant molecular biology, 82(4-5), 321-337 (2013-04-30)
Ochratoxin A (OTA) is a mycotoxin that is primarily produced by Aspergillus ochraceus and Penicillium verrucosum. This mycotoxin is a contaminant of food and feedstock worldwide and may induce cell death in plants. To investigate the dynamic growth process of
C Frizzell et al.
Toxicology letters, 217(3), 243-250 (2013-01-09)
Ochratoxin A (OTA) is a mycotoxin and extrolite of fungi which has been reported in a range of foods. This study uses mammalian reporter gene assays (RGAs) with natural steroid receptors and the H295R steroidogenesis assay to assess the endocrine

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