53439

葡萄糖酸

analytical standard

• 别名: 2-戊烯二酸
• 线性分子式: HOOCCH₂CH=CHCOOH
• CAS号: 1724-02-3
• 分子量: 130.10
• Beilstein: 1759560
• MDL编号: MFCD00002784
• UNSPSC代码: 41116107

属性

• 等级: analytical standard
• 方案: ≥96.5% (HPLC)
• 保质期: limited shelf life, expiry date on the label
• 应用: clinical testing
• 包装形式: neat
• SMILES字符串: OC(=O)C\C=C\C(O)=O
• InChI: 1S/C5H6O4/c6-4(7)2-1-3-5(8)9/h1-2H,3H2,(H,6,7)(H,8,9)/b2-1+
• InChI key: XVOUMQNXTGKGMA-OWOJBTEDSA-N

说明

一般描述

Glutaconic acid is a short chain carboxylic acid which accumulates in the physiological body fluids in patients with deficiency of glutaryl-CoA dehydrogenase leading to glutaric aciduria type 1 disorder (GA1). It finds applications as a diagnostic biomarker since it is found in increased concentrations in the urine of patients with GA1. It can be detected by gas chromatography-mass spectrometry in biological fluids including urine, cerebrospinal fluid, and serum.

应用

Glutaconic acid may be used as a standard to investigate its role in the induction of the mitochondrial permeability transition (MPT) in the isolated rat liver mitochondria in vitro.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable