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化驗
≥98.0% (UV)
mp
~145 °C (dec.)
作用方式
enzyme | inhibits
儲存溫度
−20°C
SMILES 字串
N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
InChI
1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H,11,12)/t5-/m0/s1
InChI 密鑰
YCWQAMGASJSUIP-YFKPBYRVSA-N
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一般說明
Chemical structure: amino acid derivatives
應用
Inhibits purine synthesis. An analogue of glutamine, inhibiting glutamine-requiring enzymes.
取代透過
Jun Zhao et al.
Cell metabolism, 31(5), 937-955 (2020-04-24)
Cell proliferation and inflammation are two metabolically demanding biological processes. How these competing processes are selectively executed in the same cell remains unknown. Here, we report that the enzyme carbamoyl-phosphate synthetase, aspartyl transcarbamoylase, and dihydroorotase (CAD) deamidates the RelA subunit
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