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Merck
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文件

ST1042

Sigma-Aldrich

Anti-PKD2 Rabbit pAb

liquid, Calbiochem®

别名:

Anti-Protein Kinase D2

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

包含

≤0.1% sodium azide as preservative

物種活性

human

製造商／商標名

Calbiochem®

儲存條件

OK to freeze

同型

IgG

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... PKD2(5311)

一般說明

Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~105 kDa PKD2 protein.
Recognizes the ~105 kDa PKD2 protein in HEK293 cells.
This Anti-PKD2 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of PKD2.

免疫原

Human
a synthetic peptide corresponding to amino acids near the C-terminus of human PKD2

應用


Immunoblotting (1:500-1:5000)
Immunoprecipitation (1-4 g/mg lysate)

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Highly Toxic (H)

外觀

In PBS.

重構

Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw.

分析報告

Positive Control
HEK 293 cells

其他說明

Rey, O., et al. 2003. Biochem. Biophys. Res. Commun.302, 817.
Sturany, S., et al. 2002. J. Biol. Chem.277, 29431.
Sturany, S., et al. 2001. J. Biol. Chem.276, 3310.
This antibody does not cross-react with PKD1 or PKD3. Antibody should be titrated for optimal use in individual systems.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

nwg

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Jianfen Guo et al.
The Journal of biological chemistry, 286(8), 6500-6509 (2010-12-16)
Protein kinase D (PKD) exists as a family of structurally related enzymes that are activated through similar phosphorylation-dependent mechanisms involving protein kinase C (PKC). While individual PKD isoforms could in theory mediate distinct biological functions, previous studies identify a high
Clara Aicart-Ramos et al.
The Journal of biological chemistry, 291(45), 23516-23531 (2016-09-25)
Protein kinase D (PKD) isoforms are protein kinase C effectors in signaling pathways regulated by diacylglycerol. Important physiological processes (including secretion, immune responses, motility, and transcription) are placed under diacylglycerol control by the distinctive substrate specificity and subcellular distribution of
Tim Eiseler et al.
The Journal of biological chemistry, 291(1), 462-477 (2015-10-29)
Vesicle formation and fission are tightly regulated at the trans-Golgi network (TGN) during constitutive secretion. Two major protein families regulate these processes: members of the adenosyl-ribosylation factor family of small G-proteins (ARFs) and the protein kinase D (PKD) family of
Milena Armacki et al.
Gastroenterology, 159(3), 1019-1035 (2020-05-25)
Pancreatic tumor cells release small extracellular vesicles (sEVs, exosomes) that contain lipids and proteins, RNA, and DNA molecules that might promote formation of metastases. It is not clear what cargo these vesicles contain and how they are released. Protein kinase
Christoph Wille et al.
Journal of leukocyte biology, 104(3), 615-630 (2018-04-16)
Neutrophils are important mediators of the innate immune defense and of the host response to a physical trauma. Because aberrant infiltration of injured sites by neutrophils was shown to cause adverse effects after trauma, we investigated how neutrophil infiltration could

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