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SCC007

Sigma-Aldrich

ReNcell CX人神经祖细胞系

ReNcell CX is an immortalized human neural progenitor cell line with the ability to readily differentiate into neurons & glial cells.

别名:

Human NSC Line, Human Neural Stem Cell Line, Human Neural Stem Cells

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About This Item

分類程式碼代碼:
41106509
eCl@ss:
32011203
NACRES:
NA.75

生物源

human

品質等級

100

製造商／商標名

Chemicon®
ReNcell

技術

cell culture | stem cell: suitable

輸入

sample type neural stem cell(s)

運輸包裝

liquid nitrogen

一般說明

ReNcell CX是一种永生化的人神经祖细胞系，具有易于分化为神经元和神经胶质细胞的能力。 ReNcell CX源自人胎脑的皮质区域。 通过用c-myc癌基因进行逆转录病毒转导而永生化，该细胞系在层粘连蛋白上以单层快速生长，倍增时间为20-30小时。 核型分析表明，即使经过长时间传代（>45代），ReNcell CX仍可在培养物中保留正常的二倍体核型。 ReNcell CX由ReNeuron Group plc开发，ReNeuron Group plc是一家专门将人体体干细胞用于治疗的生物技术公司。 ReNcell CX可用于多种研究应用，例如神经毒性、神经发生、电生理学、神经递质和受体功能的研究。 ReNcell CX细胞是按照法律和伦理的方式获得的，符合现行的当地知情同意程序。

ReNcell现在用于阿尔茨海默′病的3D细胞模型！
Tanzi, R and Kim, DY et. al. A three-dimensional human neural cell culture model of Alzheimer′s disease.Nature.2014 Nov 13;515(7526):274-8.
（发表在Nature上）
产品来源：人类皮质脑组织

細胞系描述

神经干细胞

應用

研究类别
干细胞研究

成分

> 1x106 活ReNcell CX细胞

品質

已经验证了每批ReNcell CX细胞的巢蛋白和Sox 2的高水平表达及其自我更新和多谱系分化能力（请参见数据表图）。 通过染色体扩散评估，细胞还显示出正常的核型，并且支原体测试为阴性。已对孕妇血液进行了HIV、HTLV、乙型和丙型肝炎筛查。

儲存和穩定性

当在推荐的储存条件（液氮）下储存时，ReNcell CX细胞在有效期内保持稳定。 请勿暴露于高温下。 到期后，请丢弃所有剩余的试剂。 我们建议在十代内使用细胞。

其他說明

根据产品文件中详述的“学术使用协议”的条款，本产品预期仅用于销售和销售给学术机构，以供内部学术研究使用。有关任何其他用途的信息，请联系[email protected]。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

仅供研究使用。在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 3

閃點（°F）

does not flash

閃點（°C）

does not flash

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Suojun Zhang et al.
International journal of oncology, 45(5), 1989-1996 (2014-09-02)
Glioma stem cells (GSCs), characterized by self-renewal, multi-potentiality and tumorigenicity, are responsible for the tumor propagation, recurrence and resistance to traditional treatments, representing a critical therapeutic target. Neural stem cells (NSCs) possess inherent tropism to brain tumor cells and inhibit
Mohammad Javadi et al.
Macromolecular bioscience, 18(2) (2017-12-14)
Biocompatible conductive tough hydrogels represent a new class of advanced materials combining the properties of tough hydrogels and biocompatible conductors. Here, a simple method, to achieve a self-assembled tough elastomeric composite structure that is biocompatible, conductive, and with high flexibility
Mia C Borlongan et al.
Neuromolecular medicine, 23(4), 540-548 (2021-04-09)
The present in vitro study showed that IL-2/IL-2R antibody complex facilitates Treg-induced neuroprotection in the oxygen glucose deprivation/reoxygenation (OGD/R) model of stroke. First, we examined the role of IL-2/IL-2R-treated Tregs in OGD/R-exposed rat primary cortical cells (PCCs), which represent the
Greg Maguire et al.
Physiological reports, 7(9), e14072-e14072 (2019-05-03)
Evidence suggests that adult stem cell types and progenitor cells act collectively in a given tissue to maintain and heal organs, such as muscle, through a release of a multitude of molecules packaged into exosomes from the different cell types.
Qi Gu et al.
Advanced healthcare materials, 5(12), 1429-1438 (2016-03-31)
Direct-write printing of stem cells within biomaterials presents an opportunity to engineer tissue for in vitro modeling and regenerative medicine. Here, a first example of constructing neural tissue by printing human neural stem cells that are differentiated in situ to
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