MABF719

Anti-CD62L (L-Selectin) Antibody (mouse), FITC, clone MEL-14

clone MEL-14, 0.5 mg/mL, from rat

• 别名: L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, Lymphocyte antigen 22, Ly-22, Lymphocyte surface MEL-14 antigen, CD62L
• UNSPSC代码: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物来源: rat
• 质量水平: 100
• 偶联物: FITC conjugate
• 抗体形式: purified antibody
• 抗体产品类型: primary antibodies
• 克隆: MEL-14, monoclonal
• 种属反应性: mouse
• 浓度: 0.5 mg/mL
• 技术: flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• 同位素/亚型: IgG2aκ
• UniProt登记号: P18337
• 运输: wet ice
• 靶向翻译后修饰: unmodified
• 基因信息: mouse ... Sell(20343)

说明

一般描述

The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.

This rat monoclonal antibody Anti-CD62L (L-Selectin) (mouse), FITC, clone MEL-14 validated for use in IP, IHC & Flow Cytometry for the detection of CD62L (L-Selectin).

质量

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 µg of this antibody detected CD62L (L-Selectin) in one million C57Bl/6 splenocytes.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: nwg
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable