MABF150E

Anti-IL-2 (mouse), PE, clone JES6-5H4 Antibody

clone JES6-5H4, from rat, PE

• 别名: Interleukin-2 (IL-2), T-cell growth factor (TCGF), IL-2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rat
• 品質等級: 100
• 共軛: PE
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: JES6-5H4, monoclonal
• 物種活性: mouse
• 包裝: antibody small pack of 25 μg
• 技術: flow cytometry: suitable
• 同型: IgG2bκ
• UniProt登錄號: P04351
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Il2(16183)

说明

一般說明

The JES6-5H4 antibody binds to mouse Interleukin-2 (IL-2), a 17 kDa cytokine that is secreted by activated T cells. This cytokine acts as an autocrine stimulatory factor for T cell proliferation, differentiation and survival, as well as being an effective activator of B cells and inducer of NK cell cytotoxic functions. IL-2 plays a key modulatory role in the differentiation of T cells toward either Th17 or T regulatory (Treg) cell types and is important for Treg cell function. The IL-2 receptor (IL-2R) is a complex consisting of an IL-2R alpha chain (CD25), along with the IL-2R beta chain (CD122) and the common gamma chain (CD132). IL-2 may also bind with low affinity to the T cell surface protein CD25 alone, although this interaction does not induce cell signaling.

應用

This rat monoclonal Anti-IL-2 Antibody (mouse), PE, clone JES6-5H4, Cat. No. MABF1510 is validated for use in Flow Cytometry, for the detection of IL-2.

品質

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.06 μg from a representative lot detected IL-2 in one million C57Bl/6 splenocytes.

其他說明

Concentration: Please refer to lot specific datasheet.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: nwg