MAB2637

Anti-Integrin beta-3 (CD61) Antibody, clone HMb3-1

clone HMb3-1, from hamster(Armenian)

• 别名: CD61 antigen, Platelet membrane glycoprotein IIIa, integrin beta chain, beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), platelet glycoprotein IIIa, GPIIIa
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: hamster (Armenian)
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: HMb3-1, monoclonal
• 物種活性: mouse
• 技術: flow cytometry: suitable; immunohistochemistry: suitable
• 同型: IgG
• NCBI登錄號: NP_058060.2
• UniProt登錄號: O54890
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Itgb3(16416)

说明

一般說明

The integrin family of cell adhesion receptors consists of several membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits. Key to these molecular interactions between the integrin receptors and their respective ligands is the recognition of the Arg-Gly-Asp (RGD) sequence, known to be present in the extracellular matrix components fibronectin, vitronectin, collagen, fibrinogen, and von Willebrand factor. The involvement of integrins in vascular proliferation, adhesion, and wound repair has been well documented.

Platelet membrane glycoprotein Integrin beta3 or CD61 (GP IIIa) forms a Ca2+-dependent heterodimer complex with GP IIb. The GP IIb-IIIa complex constitutes the fibrinogen and fibronectin receptor on stimulated platelets.

特異性

The antibody recognizes Integrin beta-3.

免疫原

Recombinant protein corresponding to mouse Integrin beta-3.

應用

Detect Integrin beta-3 (CD61) using this Anti-Integrin beta-3 (CD61) Antibody, clone HMb3-1 validated for use in FC, IH.

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH (Piali, 1995).

品質

Evaluated by Flow Cytometry on mouse bone marrow-derived cells.

Flow Cytometry Analysis: 0.1-1 µg/mL of the antibody detected Integrin beta-3 on mouse bone marrow-derived cells

標靶描述

~ 86-87 kDa

外觀

Format: Purified

分析報告

Control
Mouse bone marrow-derived cells

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable