推荐产品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
P1H4, monoclonal
物種活性
human, primate
製造商／商標名
Chemicon®
技術
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... ITGA4(3676)
特異性
整合素在血管增殖、粘附和伤口修复中的作用已被充分证明。细胞粘附受体的整合素家族由至少16种膜相关的异二聚体组成，由以非共价方式缔合的α和β亚基组成。整合素家族的结构和功能多样性基于各个α和β亚基的配对能力。单克隆抗体 MAB16983由人T淋巴细胞通过免疫生产。 该抗体可与灵长类动物和人的整合素a4 发生反应。
應用
免疫组化（优选固定剂为丙酮和醇类）
免疫细胞化学
免疫沉淀
FACS 分析
ELISA
放射性免疫测定
生物活性MAB16983 抑制CS-1 和VCAM结合。
最佳工作稀释度必须由最终用户进行确定。
免疫细胞化学
免疫沉淀
FACS 分析
ELISA
放射性免疫测定
生物活性MAB16983 抑制CS-1 和VCAM结合。
最佳工作稀释度必须由最终用户进行确定。
抗整合素α4抗体（克隆P1H4）可检测整合素α4 &水平&已有相关文献发表&经验证可用于ELISA、FC、IC、IH IP。
聯結
替代：04-1131
外觀
形式：纯化
通过蛋白 A琼脂糖™色谱纯化的免疫球蛋白。 溶于0.02M PBS （pH 7.6）、0.25M NaCl，含有 0.01% 叠氮化钠的液体。
儲存和穩定性
在+2-8C下保存。
其他說明
浓度：请参考批次特异性浓缩物的检验报告。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Sepharose is a trademark of Cytiva
Not finding the right product?
Try our 产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Marco R Schroeter et al.
Circulation research, 103(5), 536-544 (2008-07-29)
The adipocytokine leptin modulates vascular remodeling and neointima formation. Because endothelial progenitor cells (EPCs) participate in vascular repair, we analyzed the effects of leptin on human EPC function in vitro and in vivo. After 7 days in culture, EPCs expressed
Carla Danussi et al.
The Journal of cell biology, 195(1), 131-145 (2011-09-29)
EMILIN1 promotes α4β1 integrin-dependent cell adhesion and migration and reduces pro-transforming growth factor-β processing. A knockout mouse model was used to unravel EMILIN1 functions in skin where the protein was abundantly expressed in the dermal stroma and where EMILIN1-positive fibrils
Rhiannon M Kelsh-Lasher et al.
The Journal of investigative dermatology, 137(12), 2505-2512 (2017-08-27)
Alternative splicing of fibronectin increases expression of the EDA+ isoform of fibronectin (EDA+Fn), a damage-associated molecular pattern molecule, which promotes fibro-inflammatory disease through the activation of toll-like receptors. Our studies indicate that the fibronectin EDA domain drives two waves of
Rika Tanaka et al.
The Journal of biological chemistry, 284(30), 19817-19825 (2009-05-23)
Fibronectin plays important roles in erythropoiesis through the fibronectin receptors VLA-4 and VLA-5. However, the substantial role of these fibronectin receptors and their functional assignment in erythroid differentiation are not yet fully understood. Here, we investigated the effects of cell
Integrin alpha9beta1 mediates enhanced cell migration through nitric oxide synthase activity regulated by Src tyrosine kinase.
Gupta, SK; Vlahakis, NE
Journal of Cell Science null
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门