HCYTB-60K

MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel B

• 分類程式碼代碼: 12161503
• NACRES: NA.77

属性

• 用途: kit sufficient for 96 wells
• 品質等級: 200
• 物種活性: human
• 製造商／商標名: Milliplex^®
• 參數: 25 μL sample volume (per well)
• 技術: multiplexing: suitable
• 檢測方法: fluorometric (Luminex^® xMAP^®)
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C

说明

一般說明

• “Cytokine” is a general term used for a diverse group of small proteins, peptides or glycoproteins secreted by lymphocytes, monocytes, macrophages and other cells that regulate immune responses, hematopoiesis and lymphocyte development. Cytokines include interleukins, interferons, chemokines and other signaling molecules. Growth factors are extracellular polypeptides that have a positive effect on cell growth and proliferation. They can stimulate growth in a variety of different cell types. Growth factors and cytokines are similar in structure and the way of action. Individual cytokines or growth factors are produced by multiple cell types. This is different from hormones, which tend to be made by specialized glands. Each cytokine or growth factor acts through its own receptor on target cells to generate signaling pathways, and as a consequence to regulate biological processes. Some intracellular signaling components are shared between cytokines and growth factors. Expression of cytokines or growth factors and their receptors is highly regulated. De-regulation may contribute to many diseases such as infectious disease, autoimmune and chronic inflammatory disease, cardiovascular disease, metabolic syndrome, neurological disorders, and cancer. Cytokine and growth factor research plays a significant role in achieving a deeper understanding of the immune system and combating related diseases.The MILLIPLEX^® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the verification process include: cross-reactivity, dilution linearity, kit stability, and sample behavior (for example, detectability and stability).In addition, each panel and kit meet stringent manufacturing criteria to ensure batch to-batch reproducibility.
  
  The MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel B Magnetic Bead Panel enables you to focus on the therapeutic potential of cytokines and the modulation of cytokine expression. Coupled with the Luminex^® xMAP^® platform in a magnetic bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.
  
  Research Category: Inflammation & Immunology
  
  Research sub-category:
  
  Inflammation & Autoimmune Mechanisms
• Inflammation

特異性

There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

應用

The MILLIPLEX^® Human Cytokine/Chemokine/Growth Factor Panel B Magnetic Bead Panel is a 48-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: 6Ckine, sCD137, sFAS, sFASL, APRIL, BAFF, BCA-1, CCL28, CTACK, CXCL16, ENA-78, Eotaxin-2, Eotaxin-3, GCP-2, Granzyme A, Granzyme B, HMGB1, I-309, IFNβ, IFNω, IL-11, IL-16, IL-20, IL-21, IL-23, IL-24, IL-28A, IL-29, IL-31, IL-33, IL-34, IL-35, I-TAC, LIF, Lymphotactin, MCP-2, MCP-4, MIP-1δ, MIP-3α, MIP-3β, MPIF-1, Perforin, SCF, SDF-1, TARC, TPO, TRAIL, TSLP.

特點和優勢

Design your multiplex kit by choosing available analytes within this panel.

法律資訊

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 象形圖: GHS08,GHS05,GHS07,GHS09
• 訊號詞: Danger
• 危險聲明: H302 + H312 + H332,H317,H318,H373,H411
• 防範說明: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• 標靶器官: Respiratory Tract
• 儲存類別代碼: 10 - Combustible liquids