GF349

Vascular Endothelial Growth Factor 121 human

animal free, recombinant, suitable for cell culture

• 别名: VEGF, vascular endothelial growth factor
• UNSPSC代码: 12352202
• eCl@ss: 32160405
• NACRES: NA.77

属性

• 产品名称: VEGF121,; Human Recombinant Animal Free,
• 杂质: <0.1 μg/mg protein endotoxin (<1 EU/μg)
• 质量水平: 100
• UniProt登记号: P15692
• 运输: dry ice

说明

一般描述

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates.
Recombinant human VEGF121 is a 28.4 kDa disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.

质量

Determined by the dosedependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable