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生物源
rabbit
品質等級
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
horse, human, rat
物種活性(以同源性預測)
mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), equine (based on 100% sequence homology)
技術
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... CDH13(1012)
一般說明
T-钙粘蛋白(CDH13),也称钙粘蛋白13,是钙粘蛋白超家族的成员。 该蛋白与其他家族成员的不同之处在于它缺乏胞质结构域,并通过GPI锚定物锚定在细胞膜上。T-钙粘蛋白在心血管系统中广泛表达。 T-钙粘蛋白的突变与多种癌症有关。
特異性
该抗体可识别T-钙粘蛋白的钙粘蛋白1结构域。该抗体可检测~130 kDa的前蛋白和蛋白水解裂解的~105 kDa成熟同工型。(Denzel, M., et al. (2010).J Clin Invest.120(12):4342–4352.)
免疫原
KLH偶联线性肽,对应于人T-钙粘蛋白的钙粘蛋白1结构域。
表位:钙粘蛋白1结构域
應用
T-钙粘蛋白(CDH13)抗体可检测T-钙粘蛋白(CDH13)水平 & 已发表 & 经验证可用于WB、IH(P)。
免疫组化分析: 代表性批次的1:1,000稀释液在人脑和人心脏组织中检测到钙粘蛋白。
研究子类别
粘附(CAMs)
粘附(CAMs)
研究类别
细胞结构
细胞结构
品質
已通过蛋白质印迹法在人体心脏组织裂解液中进行了评估。
蛋白质印迹分析:0.1 µg/mL的该抗体在10 µg人心脏组织裂解液中检测到T-钙粘蛋白。
蛋白质印迹分析:0.1 µg/mL的该抗体在10 µg人心脏组织裂解液中检测到T-钙粘蛋白。
標靶描述
观测值为~130和~105 kDa。
~约130 kDa对应前蛋白,~105 kDa对应蛋白水解裂解的成熟同工型。(Denzel, M., et al. (2010).J Clin Invest.120(12):4342–4352.)
~约130 kDa对应前蛋白,~105 kDa对应蛋白水解裂解的成熟同工型。(Denzel, M., et al. (2010).J Clin Invest.120(12):4342–4352.)
外觀
亲和纯化
纯化的兔多克隆抗体,溶于含有0.1 M Tris-甘氨酸(pH 7.4)、150 mM NaCl和0.05%叠氮化钠的缓冲液中。
儲存和穩定性
自收到之日起,在2-8°C条件下可稳定保存1年。
分析報告
对照
人心脏组织裂解液
人心脏组织裂解液
其他說明
浓度:请参考批次特异性浓缩物的检验报告。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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