一般說明
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions. These functions include axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
免疫原
KLH-conjugated linear peptide corresponding to human Neurotrypsin.
應用
Detect the Neurotrypsin protein using this Anti-Neurotrypsin validated for use in WB & IHC.
Western Blot Analysis: 1 µg/mL from a representative lot detected Neurotrypsin in 10 µg/mL of rat testis tissue lysate.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Neurotrypsin in human midbrain and rat cerebellum tissues.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Neurotrypsin in human midbrain and rat cerebellum tissues.
品質
Evaluated by Western Blot in mouse testis tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Neurotrypsin in 10 µg/mL of mouse testis tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Neurotrypsin in 10 µg/mL of mouse testis tissue lysate.
標靶描述
~97 kDa observed. Uncharacterized bands may appear at ~13 kDa, ~38 kDa, and ~43 kDa in some lysates.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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