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AB6021

Sigma-Aldrich

Anti-Stabilin-1 Antibody, CT

from rabbit

别名:

Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1, MS-1 antigen, common lymphatic endothelial and vascular endothelial receptor-1, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger re

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

unpurified

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human

技術

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... STAB1(23166)

一般說明

Stabilin-1 and Stabilin-2 constitute a novel family of fasciclin domain-containing hyaluronan receptor homologs that may play a role in cell-cell and cell-extracellular matrix interactions in vascular function and inflammatory processes. Stabilin-1 is a transmembrane protein, expressed in endothelial cells within the sinusoidal regions of liver, spleen, and lymph tissues as well as macrophages. Stabilin-2 is absent from the latter (Politz, 2002).

特異性

Other notable species homologies include mouse (87%) and rat (83%).
The antibody recognizes the C-terminus of Stabilin-1 within the cytoplasmic region of a cell.

免疫原

Epitope: C-terminus
GST-tagged recombinant protein corresponding to the C-terminus of human Stabilin-1.

應用

Anti-Stabilin-1 Antibody, C-terminus is an antibody against Stabilin-1 for use in WB, IH(P) & IF.
Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected Stabilin-1 in human placental tertiary villi.
Immunofluorescence Analysis: A previous lot of Anti-Stabilin-1, C-terminus was shown to positively stain using immunofluorescence techniques (Kzhyshkowska, 2008).
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

品質

Evaluated by Western blot in HUVEC lysate.
Western blot Analysis: 1:1,000 dilution of this antibody detected Stabilin-1 on 10 µg of HUVEC lysate.

標靶描述

~ 275 kDa

外觀

Unpurified
Format: Unpurified
Unpurified rabbit polyclonal in serum with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at -20°C from date of receipt if stored in undiluted aliquots.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析報告

Control
HUVEC lysate.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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Nanoscale surface modifications are widely touted to improve the biocompatibility of medically relevant materials. Immune cells, such as macrophages, play a critical role in the initial healing events following implantation. To understand the response of macrophages to nanotopography better, we

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