生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
rat, mouse, bovine, human
製造商／商標名
Chemicon®
技術
immunoprecipitation (IP): suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... GABRB2(2561)
特異性
GABAA受体β2亚基。该抗体对大鼠脑膜组分中的〜50至56kDa具有特异性。
免疫原
来自大鼠GABAA受体β2亚基胞质环的MBP融合蛋白。
應用
抗GABA A受体β2抗体，细胞质环是用于IP&WB的针对GABA A受体β2的抗体。
蛋白质印迹：1：1,000
免疫沉淀：使用15 μg抗体，该抗体可免疫沉淀大鼠前脑（150μ L）十二烷基硫酸盐提取物中68%的全部GABAA受体。
最佳工作稀释度必须由最终用户进行确定。
免疫沉淀：使用15 μg抗体，该抗体可免疫沉淀大鼠前脑（150μ L）十二烷基硫酸盐提取物中68%的全部GABAA受体。
最佳工作稀释度必须由最终用户进行确定。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptors.
Ding, L; Feng, HJ; Macdonald, RL; Botzolakis, EJ; Hu, N; Gallagher, MJ
The Journal of Biological Chemistry null
Evangelos Sotiriou et al.
Journal of neuroscience research, 82(5), 690-700 (2005-11-08)
Recent data demonstrate weaker gamma-aminobutyric acid (GABA)-ergic inhibition in ventral (VH) compared with dorsal (DH) hippocampus. Therefore, we examined possible differences regarding the GABAA receptors between VH and DH as follows: 1) the expression of the GABAA receptor subunits (alpha1/2/4/5
Zechun Peng et al.
Neurochemical research, 39(6), 1104-1117 (2013-12-20)
The α4 subunit of the GABAA receptor (GABAAR) is highly expressed in the thalamus where receptors containing the α4 and δ subunits are major mediators of tonic inhibition. The α4 subunit also exhibits considerable plasticity in a number of physiological
George E Farmer et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 315(5), R972-R982 (2018-08-30)
The median preoptic nucleus (MnPO) is an integrative site involved in body fluid homeostasis, cardiovascular control, thermoregulation, and sleep homeostasis. Angiotensin II (ANG II), a neuropeptide shown to have excitatory effects on MnPO neurons, is of particular interest with regard
Jingjing Duan et al.
Frontiers in cellular neuroscience, 13, 217-217 (2019-06-25)
In the adult brain GABAA receptors (GABAARs) mediate the majority of synaptic inhibition that provides inhibitory balance to excitatory drive and controls neuronal output. In the immature brain GABAAR signaling is critical for neuronal development. However, the cell-autonomous role of
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