推荐产品
生物源
rabbit
品質等級
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
rat, human, mouse
物種活性(以同源性預測)
dog (based on 100% sequence homology)
製造商/商標名
Chemicon®
技術
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
dog ... Gjc1(490936)
human ... GJC1(10052)
mouse ... Gjc1(14615)
rat ... Gjc1(266706)
特異性
识别人类,大鼠和小鼠间隙连接蛋白45。由于序列同源性,该抗体也有望与犬间隙连接蛋白45(100%同源)发生反应。其他物种还未经测试。
免疫原
KLH偶联合成线性肽,对应于人间隙连接蛋白45的C末端附近区域。
應用
使用经验证可用于IP、WB、IH的细胞质抗间隙连接蛋白45抗体(近C端)检测间隙连接蛋白45。
外觀
形式:纯化
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Journal of animal science, 88(10), 3269-3279 (2010-06-22)
During mammalian oogenesis, intercellular communication between oocytes and the surrounding follicle cells through gap junction channels is crucial for oocyte development and maturation. The channel properties of gap junctions may be affected by the composition or combination of connexins, the
PloS one, 9(10), e109149-e109149 (2014-10-10)
Gap junction (GJ) channels have been recognized as an important mechanism for synchronizing neuronal networks. Herein, we investigated the participation of GJ channels in the pilocarpine-induced status epilepticus (SE) by analyzing electrophysiological activity following the blockade of connexins (Cx)-mediated communication.
Circulation research, 101(12), 1283-1291 (2007-10-13)
Haplodeficient mice expressing carboxyl-terminally truncated Cx43 (K258stop/KO), instead of the wild-type Cx43 isoform, reach adulthood and reveal no abnormalities in heart morphology. Here, we have analyzed the expression of K258stop protein and the morphology of gap junctions in adult hearts
Journal of the American Heart Association, 8(8), e010823-e010823 (2019-04-05)
Background Gap junction channels made of Connexin37 (Cx37) are expressed by aortic endothelial and smooth muscle cells of hypertensive mice, as well as by the renin-secreting cells of kidneys. Methods and Results To decipher whether Cx37 has any role in
Disease models & mechanisms, 11(2) (2018-01-24)
CAR-like membrane protein (CLMP), an immunoglobulin cell adhesion molecule (IgCAM), has been implicated in congenital short-bowel syndrome in humans, a condition with high mortality for which there is currently no cure. We therefore studied the function of CLMP in a
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