540217

PTP LYP Inhibitor

The PTP LYP Inhibitor controls the biological activity of PTP LYP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 别名: PTP LYP Inhibitor, (2-pyridine)(Ph)₂P-Au-Cl, HePTP Inhibitor III, PTP Inhibitor XXVIII, PTP-PEST Inhibitor
• 经验公式（希尔记法）: C₁₇H₁₄AuClNP
• 分子量: 495.69
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: DMSO: 50 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC₅₀= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Karver, M.R., et al. 2009. J. Med. Chem.52, 6912.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable