528120

PIPER - CAS 213416-70-7 - Calbiochem

A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA.

• 别名: PIPER - CAS 213416-70-7 - Calbiochem, N,Nʹ- bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV, N,Nʹ-bis[2-(1-Piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic Diimide, Telomerase Inhibitor IV
• 经验公式（希尔记法）: C₃₈H₃₆N₄O₄
• CAS号: 213416-70-7
• 分子量: 612.72
• 分類程式碼代碼: 12352200

属性

• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: dark purple
• 溶解度: 5% acetic acid: 50 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May also be useful as an antiproliferative agent.

A perylene-based ligand that potently inhibits human telomerase by binding to G-quadruplex DNA. The strongest binding site for PIPER appears to be the 3′-boundary of the G-quadruplex. Can also bind non-specifically to nucleic acids. May be useful as an antiproliferative agent.

生化／生理作用

Cell permeable: no

Primary Target
human telomerase

Product does not compete with ATP.

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

其他說明

Han, H., et al. 1999. Biochemistry38, 6981.
Fedoroff, O.Y., et al. 1998. Biochemistry 37, 12367.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable