454565

Methyl Arachidonyl Fluorophosphonate - Calbiochem

• 别名: Methyl Arachidonyl Fluorophosphonate - Calbiochem, MAFP, cPLA2α Inhibitor III
• 经验公式（希尔记法）: C₂₁H₃₆FO₂P
• 分子量: 370.48
• 分類程式碼代碼: 12352200

属性

• 化驗: ≥98% (TLC)
• 品質等級: 100
• 形狀: liquid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 運輸包裝: wet ice
• 儲存溫度: −70°C

说明

一般說明

This product has been discontinued.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not of secretory PLA₂.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not secretory PLA₂.

生化／生理作用

Cell permeable: no

Primary Target
calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

外觀

In methyl acetate.

重構

Prior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.

其他說明

Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta1302, 55.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany