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Merck
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Key Documents

371820

Sigma-Aldrich

G-Protein βγ Binding Peptide, mSIRK(L9A)

A cell-permeable, single point mutated (Leu⁹ to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK).

别名:

G-Protein βγ Binding Peptide, mSIRK(L9A), mSIRK(L9A), myr-SIRKALNIAGYPDYD-OH

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About This Item

经验公式(希尔记法):
C90H144N20O25
分子量:
1906.23
分類程式碼代碼:
12352202
NACRES:
NA.77

品質等級

化驗

≥95% (HPLC)

形狀

lyophilized solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated (hygroscopic)

顏色

white

溶解度

DMSO: 5 mg/mL

運輸包裝

ambient

儲存溫度

2-8°C

一般說明

A cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) that contains a single point mutation (Leu9 to Ala). In contrast to mSIRK (Cat. No. 371818), the mutant peptide is unable to enhance ERK1/2 phosphorylation. Useful as a negative control for mSIRK.
A cell-permeable, single point mutated (Leu9 to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK). Does not enhance ERK1/2 phosphorylation and serves as a negative control for studies involving mSIRK (Cat. No. 371818).

生化/生理作用

Cell permeable: yes
Primary Target
G-protein βγ
Product does not compete with ATP.
Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

序列

Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Ala-Gly-Tyr-Pro-Asp-Tyr-Asp-OH

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution aliquot and freeze(-20°C). Stock solutions are stable for up to 4 months at -20°C.

其他說明

Goubaeva, F., et al. 2003. J. Biol. Chem.278, 19634.
Scott, J.K., et al. 2001. EMBO J.20, 767.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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