362338

Glyco-SNAP-1 - Calbiochem

A water-soluble nitric oxide (NO) donor.

• 别名: Glyco-SNAP-1 - Calbiochem, N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
• 经验公式（希尔记法）: C₁₃H₂₃N₃O₈S
• 分子量: 381.40
• UNSPSC代码: 12352200

属性

• 质量水平: 100
• 方案: ≥96% (NMR)
• 表单: crystalline solid
• 制造商/商品名称: Calbiochem^®
• 储存条件: OK to freeze; protect from light
• 颜色: green
• 溶解性: aqueous buffer: 100 mg/mL; water: 100 mg/mL; methanol: 5 mg/mL
• 运输: ambient
• 储存温度: −20°C

说明

一般描述

A water-soluble and stable nitric oxide (NO) donor (t_½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.

A water-soluble nitric oxide (NO) donor. More stable (t_½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.

生化/生理作用

Cell permeable: no

Primary Target
A water-soluble nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

重悬

Unstable in solution; reconstitute just prior to use.

其他说明

Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable