324905

Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem

A cell-permeable antitumor antibiotic.

• 别名: Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem, 4ʹ-Epidoxorubicin, HCl
• 经验公式（希尔记法）: C₂₇H₂₉NO₁₁ · xHCl
• CAS号: 56390-09-1
• 分子量: 543.52 (free base basis)
• MDL编号: MFCD00941448
• UNSPSC代码: 12352200

属性

• 质量水平: 100
• 方案: ≥95% (HPLC)
• 表单: solid
• 制造商/商品名称: Calbiochem^®
• 储存条件: OK to freeze; desiccated (hygroscopic); protect from light
• 颜色: orange-red
• 溶解性: water: 1 mg/mL
• 运输: ambient
• 储存温度: 2-8°C
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1
• InChI key: MWWSFMDVAYGXBV-FGBSZODSSA-N

说明

一般描述

A cell-permeable, antitumor antibiotic. A stereoisomer of doxorubicin that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

This product has been discontinued.

生化/生理作用

Cell permeable: yes

Primary Target
Antitumor antibiotic

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Luck, H.J., et al. 1996. Semin. Oncol.23, 33.
Sandri, M.I., et al. 1996. Br. J. Cancer73, 1518.
Boddy, A.V., et al. 1995. Eur. J. Cancer31A, 69.
Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol.35, 257.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形图: GHS08,GHS07
• 警示用语：: Danger
• 危险声明: H302,H340,H350,H360
• 预防措施声明: P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
• 危险分类: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• 储存分类代码: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable