1.52016

Chromolith^® RP-18 endcapped (monolithic) HPLC Columns

L × I.D. 100 mm x 10 mm SemiPrep Column

• 别名: Chromolith^® SemiPrep RP-18 封端100-10柱
• 分類程式碼代碼: 41115709
• NACRES: SB.52

属性

• product name: Chromolith^® RP-18封端, L × I.D. 100 mm x 10 mm SemiPrep column
• 材料: PEEK column
• 品質等級: 100
• agency: suitable for USP L1
• 產品線: Chromolith^®
• 特點: endcapped
• 包裝: 1 ea of
• 標籤範圍: 18% Carbon loading
• 參數: 150 bar pressure; 45 °C max. temp.
• 技術: HPLC: suitable (Semi Prep HPLC); LC/MS: suitable
• 柱長度 × 內徑: 10 cm × 10 mm
• 基質: monolithic silica
• 基質活性組: C18 bonding phase
• 孔徑: 13 nm mesoporosity; 2 μm macroporosity
• 工作pH值範圍: 2-7.5
• 分離技術: reversed phase
• 儲存溫度: no temp limit

说明

一般說明

Chromolith^® SemiPrep RP-18封端HPLC色谱柱非常适合从分析到半制备柱的直接放大。这是因为与填充5 μm颗粒的半制备柱相比，它们在较低的操作压力下提供更快的样品吞吐量。Chromolith^® SemiPrep 10 mm内径色谱柱结合了高分离速度和优异的性能。这使得它们成为10 mm内径（甚至21.2mm内径）颗粒柱的完美替代品。它们具有与Chromolith^®分析柱相同的双峰多孔硅棒结构，内径为4.6 mm。其大孔直径为2 μm，中孔直径为13 nm。这种组合大大减少了分离时间，同时提高了效率。

革命性的整体二氧化硅具有独特的大孔和中孔组合，实现了：
—在极低的柱背压下快速分离
—高矩阵公差，通过简化工作流程节省时间和成本
—色谱柱寿命延长节省了成本

推荐的保护柱有：
Chromolith^® SemiPrep RP-18封端10-10保护柱（3件）[1.52036]，带Chromolith^®保护柱支架10 mm x 10 mm [1.52037]

了解更多：
手册：在任何系统上加速分离。Chromolith^®整体二氧化硅HPLC色谱柱

應用

• Simultaneous determination of eight arginine-related metabolites in cellular extracts using liquid chromatography-tandem mass spectrometry.: This study explores the usage of the Chromolith^® RP-18 endcapped column for precise metabolic profiling, showcasing its effectiveness in analyzing arginine-related metabolites with high resolution and throughput (Amatya et al., 2020).


• Rapid Determination of 30 Polyphenols in Tongmai Formula, a Combination of Puerariae Lobatae Radix, Salviae Miltiorrhizae Radix et Rhizoma, and Chuanxiong Rhizoma, via Liquid Chromatography-Tandem Mass Spectrometry.: The use of Chromolith^® RP-18 endcapped allowed for the fast and efficient separation of polyphenols in complex herbal formulations, illustrating its capabilities in herbal chemistry applications (Wang et al., 2017).


• Simultaneous Liquid Chromatographic Determination of Ebastine with Two Sympathomimetic Drugs Using a Monolithic Column.: This research highlights the Chromolith^® RP-18 endcapped column′s ability to simultaneously analyze multiple compounds, thereby providing a method that improves the efficiency of pharmaceutical analyses (Ibrahim and Wahba, 2017).

分析報告

碳含量：18.0 - 22.0 %
压力：≤30 bar
性能（蒽）
理论塔板数（N/m）（蒽）：≥80000
容量系数（蒽）：4.3 - 5.0
拖尾因子（USP）：0.90 - 1.45 %
选择性
分离因子（蒽/孕酮）：1.95 - 2.35

法律資訊

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany