推荐产品
生物源
human
品質等級
重組細胞
expressed in baculovirus infected Sf21 cells
分子量
Mw 80 kDa
製造商/商標名
Upstate®
技術
activity assay: suitable (kinase)
NCBI登錄號
UniProt登錄號
基因資訊
human ... PRKG1(5592)
一般說明
N末端6个His标签,重组,全长PKG1α。
产品来源:PKG1α,由杆状病毒在Sf21细胞中表达获得。
應用
研究类别
炎症 & 免疫学
炎症 & 免疫学
生化/生理作用
蛋白质靶标:PKG1α
靶标亚家族:AGC
品質
通常通过PAKtide(RRRLSFAEPG)的磷酸化进行评估。
外觀
Ni2+/NTA-琼脂糖
儲存和穩定性
自发货之日起可在-70°C保存6个月
其他說明
比活相关数据,请参阅分析证书以获取该酶的单独批次。
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Physiology and pathophysiology of vascular signaling controlled by guanosine 3',5'-cyclic monophosphate-dependent protein kinase.
Birschmann, Ingvild and Walter, Ulrich
Acta Biochimica Polonica, 51, 397-404 (2004)
Sequential activation of soluble guanylate cyclase, protein kinase G and cGMP-degrading phosphodiesterase is necessary for proper induction of long-term potentiation in CA1 of hippocampus. Alterations in hyperammonemia.
Monfort, Pilar, et al.
Neurochemistry International, 45, 895-901 (2004)
Mary G Johlfs et al.
PloS one, 10(7), e0132105-e0132105 (2015-07-02)
Profiling cellular proteome is critical to understanding signal integration during cell fate determination. In this study, the capability of capillary isoelectric focusing (cIEF) immunoassays to detect post-translational modifications (PTM) of protein isoforms is demonstrated. cIEF immunoassays exhibit protein detection sensitivity
Modulation of synaptic function by cGMP and cGMP-gated cation channels.
Barnstable, Colin J, et al.
Neurochemistry International, 45, 875-884 (2004)
Zhenyu Li et al.
Cell, 112(1), 77-86 (2003-01-16)
It is currently accepted that cGMP-dependent protein kinase (PKG) inhibits platelet activation. Here, we show that PKG plays an important stimulatory role in platelet activation. Expression of recombinant PKG in a reconstituted cell model enhanced von Willebrand factor (vWF)-induced activation
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