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生物源
mouse
品質等級
重組細胞
expressed in E. coli
分子量
Mw 65 kDa
製造商／商標名
Upstate®
技術
activity assay: suitable (kinase)
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
基因資訊
mouse ... MAP2K4(26398)
一般說明
Product Source: expressed in E. coli
Recombinant mouse MKK4, corresponding to amino acids 35-397, fused to an Nterminal GST-tag
生化／生理作用
Protein Target: MKK4
Target Sub-Family: STE
品質
routinely evaluated by phosphorylation of ATF2 substrate
外觀
GSH-agarose chromatography
儲存和穩定性
6 months at -20C
其他說明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
Eleanore A Gross et al.
The Journal of biological chemistry, 277(16), 13873-13882 (2002-02-12)
Mitogen-activated protein (MAP) kinase pathways are three-kinase modules that mediate diverse cellular processes and have been highly conserved among eukaryotes. By using a functional complementation screen in yeast, we have identified a human MAP kinase kinase kinase (MAPKKK) that shares
Luis Cedeno-Rosario et al.
The Journal of biological chemistry, 298(8), 102263-102263 (2022-07-18)
Mixed lineage kinase 3 (MLK3) is a serine/threonine mitogen-activated protein kinase kinase kinase that promotes the activation of multiple mitogen-activated protein kinase pathways and is required for invasion and proliferation of ovarian cancer cells. Inhibition of MLK activity causes G2/M
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