110175-M

Acetyl-Pepstatin

An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (K_i = 20 nM at pH 4.7) and HIV-2 proteinase (K_i = 5 nM at pH 4.7).

• 别名: Acetyl-Pepstatin, Ac-Val-Val-(3S,4S)-Sta-Ala-(3S,4S)-Sta-OH
• 经验公式（希尔记法）: C₃₁H₅₇N₅O₉
• CAS号: 28575-34-0
• 分子量: 643.81
• 分類程式碼代碼: 12352202

属性

• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: 50% acetic acid: 5 mg/mL
• 儲存溫度: −20°C
• InChI: 1S/C31H57N5O9/c1-15(2)11-21(35-30(44)28(18(7)8)36-31(45)27(17(5)6)33-20(10)37)23(38)13-25(40)32-19(9)29(43)34-22(12-16(3)4)24(39)14-26(41)42/h15-19,21-24,27-28,38-39H,11-14H2,1-10H3,(H,32,40)(H,33,37)(H,34,43)(H,35,44)(H,36,45)(H,41,42)/t19-,21-,22-,23-,24-,27-,28-/m0/s1
• InChI 密鑰: WKYBEGDEGRCZNF-LBTYKNIQSA-N

说明

一般說明

An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (K_i = 20 nM at pH 4.7) and HIV-2 proteinase (K_i = 5 nM at pH 4.7).

An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (K_i = 20 nM at pH 4.7) and HIV-2 proteinase (K_i = 5 nM at pH 4.7). Acts as a substrate-analog inhibitor.

生化／生理作用

Primary Target
HIV-1 proteinase

Target K_i: 20 nM at pH 4.7 against HIV-1 proteinase

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

其他說明

Ulrich, B., et al. 2000. Protein Sci.9, 2232.
Song, K., et al. 1992. Kidney Int.42, 639.
Richards, A.D., et al. 1989. FEBS Lett. 247, 113.
Richards, A.D., et al. 1989. FEBS Lett. 253, 214.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable