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Merck
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文件

09-814

Sigma-Aldrich

抗-二甲基精氨酸抗体,非对称性(ASYM25)

serum, from rabbit

别名:

dimethyl-arginine, asymmetric

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse

物種活性(以同源性預測)

rat (based on 100% sequence homology), human (based on 100% sequence homology)

技術

western blot: suitable

運輸包裝

wet ice

目標翻譯後修改

unmodified

一般說明

不对称二甲基化精氨酸(ADMA)是一种内源性L-精氨酸代谢产物,由含有甲基化精氨酸的蛋白质的蛋白水解产生,并且是一氧化氮合酶(NOS)的已知抑制剂。在各种研究中,已经观察到ADMA在细胞运动和肌动蛋白细胞骨架中具有调节作用。ADMA水平升高与散发性FSGS、冠状动脉疾病、高血压、外周动脉闭塞性疾病、肥胖、卒中、先兆子痫和糖尿病肾病患者的心血管死亡率/发病率相关。

特異性

该抗体可识别二甲基化精氨酸。

免疫原

含有不对称二甲基-精氨酸-甘氨酸重复序列的KLH偶联线性肽。

應用

使用经验证可用于WB的不对称性抗二甲基精氨酸抗体(ASYM25)检测二甲基精氨酸。

品質

已通过蛋白质印迹法在经PRMT1处理和未经处理的MEF细胞裂解液中进行了评估。

蛋白质印迹分析:该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。

標靶描述

多个。 该抗体可检测含有不对称二甲基化精氨酸的蛋白质。

分析報告

对照
经PRMT1处理和未处理的MEF细胞裂解液

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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