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生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse
物種活性(以同源性預測)
rat (based on 100% sequence homology), human (based on 100% sequence homology)
技術
western blot: suitable
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
不对称二甲基化精氨酸(ADMA)是一种内源性L-精氨酸代谢产物,由含有甲基化精氨酸的蛋白质的蛋白水解产生,并且是一氧化氮合酶(NOS)的已知抑制剂。在各种研究中,已经观察到ADMA在细胞运动和肌动蛋白细胞骨架中具有调节作用。ADMA水平升高与散发性FSGS、冠状动脉疾病、高血压、外周动脉闭塞性疾病、肥胖、卒中、先兆子痫和糖尿病肾病患者的心血管死亡率/发病率相关。
特異性
该抗体可识别二甲基化精氨酸。
免疫原
含有不对称二甲基-精氨酸-甘氨酸重复序列的KLH偶联线性肽。
應用
使用经验证可用于WB的不对称性抗二甲基精氨酸抗体(ASYM25)检测二甲基精氨酸。
品質
已通过蛋白质印迹法在经PRMT1处理和未经处理的MEF细胞裂解液中进行了评估。
蛋白质印迹分析:该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
蛋白质印迹分析:该抗体的1:1,000稀释液在10 µg 经PRMT1处理和未处理的MEF细胞裂解液上检测到二甲基化精氨酸。
標靶描述
多个。 该抗体可检测含有不对称二甲基化精氨酸的蛋白质。
分析報告
对照
经PRMT1处理和未处理的MEF细胞裂解液
经PRMT1处理和未处理的MEF细胞裂解液
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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