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Merck
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文件

07-318

Sigma-Aldrich

Anti-TBX2 Antibody

serum, Upstate®

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, human

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

基因資訊

human ... TBX2(6909)

特異性

TBX2

免疫原

GST fusion protein corresponding to residues 554-702 of human TBX2

應用

Detect TBX2 also known as T-box 2 with Anti-TBX2 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in IP & WB.

品質

routinely evaluated by immunoblot on RIPA lysates from MCF-7 human breast adenocarcinoma cells

標靶描述

74kDa

外觀

antiserum with 0.05% sodium azide before the addition of glycerol to 30%

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Juan Aparicio-Blanco et al.
Drug delivery and translational research (2024-05-13)
Brain drug delivery is severely hindered by the presence of the blood-brain barrier (BBB). Its functionality relies on the interactions of the brain endothelial cells with additional cellular constituents, including pericytes, astrocytes, neurons, or microglia. To boost brain drug delivery
J J Jacobs et al.
Nature genetics, 26(3), 291-299 (2000-11-04)
To identify new immortalizing genes with potential roles in tumorigenesis, we performed a genetic screen aimed to bypass the rapid and tight senescence arrest of primary fibroblasts deficient for the oncogene Bmi1. We identified the T-box member TBX2 as a
Timo H Lüdtke et al.
Respiratory research, 22(1), 85-85 (2021-03-19)
Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was traced to direct repression of
Chen-Leng Cai et al.
Development (Cambridge, England), 132(10), 2475-2487 (2005-04-22)
Mutations in T-box genes are the cause of several congenital diseases and are implicated in cancer. Tbx20-null mice exhibit severely hypoplastic hearts and express Tbx2, which is normally restricted to outflow tract and atrioventricular canal, throughout the heart. Tbx20 mutant
K L Redmond et al.
Oncogene, 29(22), 3252-3262 (2010-03-30)
T-box 2 (TBX2) is a transcription factor involved in mammary development and is known to be overexpressed in a subset of aggressive breast cancers. TBX2 has previously been shown to repress growth control genes such as p14(ARF) and p21(WAF1/cip1). In

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