推荐产品
生物源
rabbit
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse, human
製造商／商標名
Upstate®
技術
immunoprecipitation (IP): suitable
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... LAT(27040)
mouse ... Lat(16797)
特異性
Recognizes both forms of LAT.
免疫原
GST-tagged fusion protein corresponding to residues 31-233 of human LAT
應用
Anti-LAT Antibody detects level of LAT & has been published & validated for use in IP & WB.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
品質
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells
標靶描述
36/38 kDa
外觀
Protein A purified
Format: Purified
Protein A Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, and 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析報告
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.
Wange, R L, et al.
The Journal of Biological Chemistry, 270, 18730-18733 (1995)
B S Wilson et al.
The Journal of cell biology, 154(3), 645-658 (2001-08-08)
In mast cells, cross-linking the high-affinity IgE receptor (Fc(epsilon)RI) initiates the Lyn-mediated phosphorylation of receptor ITAMs, forming phospho-ITAM binding sites for Syk. Previous immunogold labeling of membrane sheets showed that resting Fc(epsilon)RI colocalize loosely with Lyn, whereas cross-linked Fc(epsilon)RI redistribute
T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha.
Clark, JM; Annenkov, AE; Panesar, M; Isomaki, P; Chernajovsky, Y; Cope, AP
Proceedings of the National Academy of Sciences of the USA null
T Harder et al.
The Journal of cell biology, 151(2), 199-208 (2000-10-19)
Activation of T cell antigen receptor (TCR) induces tyrosine phosphorylations that mediate the assembly of signaling protein complexes. Moreover, cholesterol-sphingolipid raft membrane domains have been implicated to play a role in TCR signal transduction. Here, we studied the assembly of
Assessment of caspase mediated degradation of linker for activation of T cells (LAT) at a single cell level.
Klossowicz, Mikolaj, et al.
Journal of Immunological Methods, 389, 9-17 (2013)
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