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Merck
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文件

04-901

Sigma-Aldrich

抗 NR2A 抗体,克隆 A12W,兔单克隆

culture supernatant, clone A12W, Upstate®

别名:

Anti-EPND, Anti-FESD, Anti-GluN2A, Anti-LKS, Anti-NMDAR2A, Anti-NR2A

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

A12W, monoclonal

物種活性

mouse, rat

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... GRIN2A(2903)

特異性

NR2A

免疫原

带有6His标签的融合蛋白,对应于小鼠NMDA受体2A(NR2A)的氨基酸1265-1464

應用

抗NR2A抗体,克隆A12W是针对NR2A的抗体,用于WB。
研究子类别
神经递质 & 受体
研究类别
神经科学

品質

已通过免疫印迹对大鼠脑微粒体制剂(目录号12-144)进行常规评估

標靶描述

Mr 170kDa

外觀

0.05% 叠氮化钠中的培养上清液

儲存和穩定性

自收到之日起,在-20°C条件下可稳定保存1年。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析证书(COA)

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Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Kiraly, DD; Lemtiri-Chlieh, F; Levine, ES; Mains, RE; Eipper, BA
The Journal of Neuroscience null
Marie Lise Frandemiche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6084-6097 (2014-04-25)
Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's
Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging.
Suzuki, Y; Goetze, TA; Stroebel, D; Balasuriya, D; Yoshimura, SH; Henderson, RM; Paoletti et al.
The Journal of Biological Chemistry null
José Gulfo et al.
PloS one, 16(2), e0246930-e0246930 (2021-02-17)
Corticosteroid-binding globulin (CBG) is the specific carrier of circulating glucocorticoids, but evidence suggests that it also plays an active role in modulating tissue glucocorticoid activity. CBG polymorphisms affecting its expression or affinity for glucocorticoids are associated with chronic pain, chronic
Dongdong Li et al.
Experimental neurology, 230(2), 302-310 (2011-05-31)
Continuous exposure of cultured cortical neurons to moderate hypoxia (1% O(2)) elevates cellular accumulation of hypoxia-inducible factor-1α (HIF-1α) and improves basal survival of cultured cortical neurons. We examined the effects of adaptation to moderate hypoxia on the vulnerability of cultured

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