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Merck
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文件

04-539

Sigma-Aldrich

Anti-MAPKAP-K2 Antibody, clone 7H4.2

clone 7H4.2, Upstate®, from mouse

别名:

MAPK-activated protein kinase 2, MAPKAP kinase 2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

7H4.2, monoclonal

物種活性

human, rat, mouse

製造商／商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

NM_004759.3
NM_032960.2

UniProt登錄號

P49137

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... MAPKAPK2(9261)

免疫原

KLH-conjugated synthetic peptide of the C-terminus of the long form of human MAPKAP-K2.

應用

Suggested dilutions:
Immunoblot Analysis: 1:500
Immunoprecipitation: 1:20
Anti-MAPKAP-K2 Antibody, clone 7H4.2 detects level of MAPKAP-K2 & has been published & validated for use in IP & WB.
Research Category
Signaling
Research Sub Category
MAP Kinases

Kinases & Phosphatases

品質

Routinely evaluated by immunoblot.

標靶描述

45 kDa

外觀

Protein A purified
200 µg (1 mg/mL) of mouse monoclonal IgG in PBS containing 0.1% sodium azide.
Format: Purified

儲存和穩定性

2 years at -20°C from date of shipment.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Isaac A Manke et al.
Molecular cell, 17(1), 37-48 (2005-01-05)
The cellular response to DNA damage is mediated by evolutionarily conserved Ser/Thr kinases, phosphorylation of Cdc25 protein phosphatases, binding to 14-3-3 proteins, and exit from the cell cycle. To investigate DNA damage responses mediated by the p38/stress-activated protein kinase (SAPK)
Ainsley A Culbert et al.
The Journal of biological chemistry, 281(33), 23658-23667 (2006-06-16)
MAPK-activated protein kinase 2 (MAPKAP K2 or MK2) is one of several kinases directly regulated by p38 MAPK. A role for p38 MAPK in the pathology of Alzheimer disease (AD) has previously been suggested. Here, we provide evidence to suggest
Matthieu Lemaire et al.
Cell cycle (Georgetown, Tex.), 5(15), 1649-1653 (2006-07-25)
CDC25B is one of the three human phosphatases that are involved in the control of the activation of cyclin-dependent kinases. CDC25B participates in regulating entry into mitosis and appears to play a key role in the checkpoint response to DNA
L Xu et al.
Oncogene, 25(21), 2987-2998 (2006-01-13)
Although cell invasion is a necessary early step in cancer metastasis, its regulation is not well understood. We have previously shown, in human prostate cancer, that transforming growth factor beta (TGFbeta)-mediated increases in cell invasion are dependent upon activation of

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