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Merck

B-043

Supelco

Brompheniramine maleate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C20H23BrN2O4
CAS号:
分子量:
435.31
EC號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

形狀

liquid

特點

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

1.0 mg/mL in methanol (as free base)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

pharmaceutical (small molecule)

格式

single component solution

儲存溫度

−20°C

SMILES 字串

OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccc(Br)cc1)c2ccccn2

InChI

1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI 密鑰

SRGKFVAASLQVBO-BTJKTKAUSA-N

基因資訊

human ... HRH1(3269)

一般說明

Brompheniramine is an over-the-counter antihistamine sold under the trade names Bromfed®, Dimetapp®, and Lodrane®. The drug is indicated for treatment of the common cold and allergic rhinitis symptoms including runny nose and itchy eyes. This Snap-N-Spike® Reference Solution is suitable for use as starting material in calibrators or controls for LC/MS or GC/MS methods in clinical toxicology, forensic analysis, and pharmaceutical research.

法律資訊

Bromfed is a registered trademark of Wockhardt EU Operations Swiss AG
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Dimetapp is a registered trademark of Wyeth LLC
Lodrane is a registered trademark of ECR Pharmaceuticals Co., Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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Ahmed S Zidan et al.
Journal of pharmaceutical sciences, 101(4), 1450-1461 (2012-01-04)
The objective of the current study was to evaluate the performance of Raman and near-infrared (NIR) techniques combined with chemometrics in characterizing the critical quality attributes of brompheniramine (BP)-tannate complexes. Seven complexes were prepared and evaluated for chemical interactions, solubilities
Silvia Tardioli et al.
The journal of physical chemistry. B, 116(24), 7033-7039 (2012-05-23)
Binding of the antihistamine drug brompheniramine (BPA) to human serum albumin (HSA) is studied by measuring quenching of the fluorescence and room temperature phosphorescence (RTP) of tryptophan. The modified Stern-Volmer equation was used to derive association constants and accessible fractions
Rachel Walsh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(30), 3523-3530 (2011-10-11)
A novel non-stabilised aqueous suspension polymerisation methodology for the preparation of spherical molecularly imprinted polymers is described with chlorpheniramine (CP), d-chlorpheniramine (d-CP), brompheniramine (BP) and d-brompheniramine (d-BP) as the templates, respectively. Using this rapid and simple technique, controlled polymer beads
Laura R Sadofsky et al.
Experimental lung research, 34(10), 681-693 (2008-12-17)
American guidelines, unlike European guidelines, support the use of antihistamines as a first line of treatment for some causes of chronic cough. Transient receptor potential vanilloid-1 (TRPV1) is an ion channel activated by the tussive agents capsaicin, resiniferatoxin, and protons.
Giorgia De Paoli et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(31), 3771-3774 (2011-11-08)
The increased availability of new psychoactive substances ("legal highs") from retail shops or internet sources has caught the imagination of consumers, law enforcement and scientific communities. The present study describes the identification of 2-(diphenylmethyl)pyrrolidine (DPMP, desoxy-D2PM) as the key constituent

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