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Merck

LM1104

Avanti

17:0-14:1 PE

Avanti Research - A Croda Brand

别名:

1-十七酰-2-(9Z-十四烯酰)-sn-甘油-3-磷酸乙醇胺

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About This Item

经验公式(希尔记法):
C36H70NO8P
分子量:
675.92
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM1104-1EA)

製造商/商標名

Avanti Research - A Croda Brand

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCC)=O)COC(CCCCCCCCCCCCCCCC)=O

一般說明

磷酸乙醇胺(PE)充当磷脂酰胆碱和磷脂酰乙醇胺合成的母体化合物。

應用

17:0-14:1 PE或1-十七烷酰基-2-(9Z-十四烯酰基)-sn-甘油-3-磷酸乙醇胺已用作内标:
  • 用于使用液相色谱-质谱(LC-MS)进行脂质定量),
  • 用于通过串联质谱(MS/MS)(与脂质组分析有关)检测脂质
  • 使用MTBE方案的脂质提取

生化/生理作用

已知磷酸乙醇胺(PE)在体内显示出广泛的抗肿瘤作用并阻止肿瘤增殖。合成PE抑制肺转移。

包裝

2mL琥珀色玻璃密封安瓿(LM1104-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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Mathieu Frechin et al.
Nature, 523(7558), 88-91 (2015-05-27)
Cells sense the context in which they grow to adapt their phenotype and allow multicellular patterning by mechanisms of autocrine and paracrine signalling. However, patterns also form in cell populations exposed to the same signalling molecules and substratum, which often
Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour
Frechin M. et al.
Nature, 523(7558), 88-91 (2015)
Kallol Gupta et al.
Nature protocols, 13(5), 1106-1120 (2018-04-28)
With the recent success in determining membrane protein structures, further detailed understanding of the identity and function of the bound lipidome is essential. Using an approach that combines high-energy native mass spectrometry (HE-nMS) and solution-phase lipid profiling, this protocol can
Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
A K Ferreira et al.
British journal of cancer, 109(11), 2819-2828 (2013-11-10)
We recently showed that synthetic phosphoethanolamine reduces tumour growth and inhibits lung metastasis in vivo. Here, we investigated its anti-leukaemia effects using acute promyelocytic leukaemia (APL) as a model. Cytotoxic effects of Pho-s on leukaemia cells were evaluated by MTT

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