890900O

ALC-0315

Avanti Research^™ - A Croda Brand

• 别名: ALC 0315, 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-aminium
• 经验公式（希尔记法）: C₄₈H₉₅NO₅
• 分子量: 766.27
• MDL號碼: MFCD33402175
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 形狀: oil
• 包裝: pkg of 1x1 g (890900O-1G); pkg of 1x100 mg (890900O-100MG); pkg of 1x200 mg (890900O-200MG); pkg of 1x25 mg (890900O-25MG); pkg of 1x50 mg (890900O-50MG); pkg of 1x500 mg (890900O-500MG)
• 製造商／商標名: Avanti Research^™ - A Croda Brand
• 技術: thin layer chromatography (TLC): suitable
• 應用: advanced drug delivery
• 脂質類型: cationic lipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: O=C(C(CCCCCC)CCCCCCCC)OCCCCCCN(CCCCO)CCCCCCOC(C(CCCCCCCC)CCCCCC)=O
• InChI: 1S/C48H95NO5/c1-5-9-13-17-19-27-37-45(35-25-15-11-7-3)47(51)53-43-33-23-21-29-39-49(41-31-32-42-50)40-30-22-24-34-44-54-48(52)46(36-26-16-12-8-4)38-28-20-18-14-10-6-2/h45-46,50H,5-44H2,1-4H3
• InChI 密鑰: QGWBEETXHOVFQS-UHFFFAOYSA-N

说明

應用

• Cationic Lipid Pairs Enhance Liver-to-Lung Tropism of Lipid Nanoparticles for In Vivo mRNA Delivery.: ALC-0315 plays a critical role in this study, enhancing the delivery efficiency of mRNA therapies from liver to lung. This research could lead to improved treatment options for various pulmonary diseases (Zeng et al., 2024).


• Engineering LNPs with polysarcosine lipids for mRNA delivery.: Demonstrates ALC-0315′s application in designing lipid nanoparticles that efficiently deliver mRNA, showcasing potential advancements in gene therapy (Kang et al., 2024).


• Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.: Utilizes ALC-0315 in the development of lipid nanoparticles that activate under tumor-specific conditions to deliver immunotherapeutic agents, offering a targeted approach to cancer treatment (Jiang et al., 2024).

包裝

• 5 mL Amber Glass Screw Cap Vial (890900O-25MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-50MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-100MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-200MG)
• 5 mL Amber Glass Screw Cap Vial (890900O-500MG)
• 30 mL Amber Glass Screw Cap Vial(890900O-1G)

其他說明

Quantities limited to 50G in a calendar year per customer.

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable