870865P

BMP22

Avanti Research^™ - A Croda Brand, powder

• 别名: 4-pentadecylbenzylphosphonic acid
• 经验公式（希尔记法）: C₂₂H₃₉O₃P
• CAS号: 1306684-90-1
• 分子量: 382.52
• MDL编号: MFCD34790773
• UNSPSC代码: 12352211
• NACRES: NA.25

属性

• 方案: 99% (TLC)
• 表单: powder
• 包装: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• 制造商/商品名称: Avanti Research^™ - A Croda Brand
• 脂质类型: bioactive lipids
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1
• InChI key: XWVBRTAQHMKHCE-UHFFFAOYSA-N

说明

一般描述

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

生化/生理作用

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

包装

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable