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Merck

860640P

Avanti

鞘氨醇(d17:1)

Avanti Research - A Croda Brand 860640P, powder

别名:

D-赤型-鞘氨醇(C17碱)

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About This Item

经验公式(希尔记法):
C17H35NO2
CAS号:
分子量:
285.47
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (860640P-10mg)
pkg of 1 × 5 mg (860640P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 860640P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCC

InChI

1S/C17H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h13-14,16-17,19-20H,2-12,15,18H2,1H3/b14-13+/t16-,17+/m0/s1

InChI 密鑰

RBEJCQPPFCKTRZ-LHMZYYNSSA-N

一般說明

鞘氨醇(d17:1)或D-赤型鞘氨醇是一种17碳鞘脂,存在于人体皮肤中。它比天然存在的C18-鞘氨醇少一个碳。

應用

鞘氨醇(d17:1)已被用作脂质标准品,用于通过液相色谱-质谱(LC-MS)和串联质谱法分析鞘脂。

生化/生理作用

鞘氨醇充当鞘氨醇-1-磷酸(S1P)的前体。鞘氨醇C-17用作通过光谱法分析鞘脂的内标物。

包裝

5 mL棕色玻璃螺旋盖小瓶(860640P-10mg)
5 mL棕色玻璃螺旋盖小瓶(860640P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析证书(COA)

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Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines
Stewart ME and Downing DT
The Journal of Investigative Dermatology, 105(4), 613-618 (1995)
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
Schull S, et al.
Cell Death & Disease, 6(3), e1691-e1691 (2015)
A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia
Paugh SW, et al.
Blood, 112(4), 1382-1391 (2008)
Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells
Apraiz A, et al.
BMC Cancer, 11(1), 477-477 (2011)
Guang-Yi Dai et al.
The Journal of biological chemistry, 295(3), 717-728 (2019-12-11)
Cellular membranes contain many lipids, some of which, such as sphingolipids, have important structural and signaling functions. The common sphingolipid glucosylceramide (GlcCer) is present in plants, fungi, and animals. As a major plant sphingolipid, GlcCer is involved in the formation

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