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Merck
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文件

860587P

Avanti

18:1 鞘磷脂/SM (d18:1/18:1(9Z))

Avanti Research™ - A Croda Brand 860587P, powder

别名:

N-油酰-D-赤型-鞘氨醇磷酸胆碱

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About This Item

经验公式（希尔记法）:
C41H81N2O6P
CAS号:
108392-10-5
分子量:
729.07
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 5 mg (860587P-5mg)

製造商／商標名

Avanti Research™ - A Croda Brand 860587P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

InChI

1S/C41H81N2O6P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-41(45)42-39(38-49-50(46,47)48-37-36-43(3,4)5)40(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,32,34,39-40,44H,6-19,22-31,33,35-38H2,1-5H3,(H-,42,45,46,47)/b21-20-,34-32+/t39-,40+/m0/s1

InChI 密鑰

NBEADXWAAWCCDG-QDDWGVBQSA-N

相关类别

一般說明

18:1 SM鞘磷脂(d18:1/18:1(9Z))是一种鞘磷脂(SM)，含一个C16神经酰胺碱基和一条酰胺连接的油酰(18:1)链。

應用

18:1 SM鞘磷脂((d18:1/18:1(9Z))可用于：
  • 作为脂质体组分分析ostreolysin A(OlyA)结合，用于研究磷脂酰胆碱(PC)对鞘磷脂(SM)/胆固醇相互作用的影响
  • 作为鞘磷脂比率定量的标准品
  • 通过表面等离子共振(SPR)技术研究其对C2结构域突变的影响

包裝

2 mL棕色玻璃密封安瓿(860587P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Yoshinori Hirano et al.
eLife, 8 (2019-05-03)
Ca2+-stimulated translocation of cytosolic phospholipase A2α (cPLA2α) to the Golgi induces arachidonic acid production, the rate-limiting step in pro-inflammatory eicosanoid synthesis. Structural insights into the cPLA2α preference for phosphatidylcholine (PC)-enriched membranes have remained elusive. Here, we report the structure of
Ayman J Aljohani et al.
Investigative ophthalmology & visual science, 55(6), 3413-3422 (2014-05-03)
We determined the profiles of sphingomyelin, sphingoid base, sphingoid base-1-phosphate, and ceramide, and their quantitative differences between control and glaucomatous trabecular meshwork (TM) derived from human donors. Control and primary open angle glaucoma (POAG) TM samples were collected from cadaver
Elisabetta Albi et al.
International journal of molecular sciences, 15(7), 11555-11565 (2014-07-01)
Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been
Shreya Endapally et al.
Cell, 176(5), 1040-1053 (2019-02-05)
Sphingomyelin and cholesterol are essential lipids that are enriched in plasma membranes of animal cells, where they interact to regulate membrane properties and many intracellular signaling processes. Despite intense study, the interaction between these lipids in membranes is not well
Delphine Milhas et al.
FEBS letters, 584(9), 1887-1894 (2009-10-28)
The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at the PM by enzymes such as sphingomyelinase (SMase) and
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