860504P

C4 Ceramide (d18:1/4:0)

Avanti Research^™ - A Croda Brand 860504P, powder

• 别名: N-butyroyl-D-erythro-sphingosine
• 经验公式（希尔记法）: C₂₂H₄₃NO₃
• CAS号: 74713-58-9
• 分子量: 369.58
• MDL编号: MFCD02259135
• UNSPSC代码: 12352211
• NACRES: NA.25

属性

• 表单: powder
• 包装: pkg of 1 × 5 mg (860504P-5mg)
• 制造商/商品名称: Avanti Research^™ - A Croda Brand 860504P
• 脂质类型: sphingolipids
• 运输: dry ice
• 储存温度: −20°C
• SMILES字符串: OC[C@]([H])(NC(CCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C22H43NO3/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-21(25)20(19-24)23-22(26)17-4-2/h16,18,20-21,24-25H,3-15,17,19H2,1-2H3,(H,23,26)/b18-16+/t20-,21+/m0/s1
• InChI key: UCBLGIBMIAFISC-CQLAPORSSA-N

说明

一般描述

C4 Ceramide (d18:1/4:0) or N-butyroyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with butyric acid. It is a non-toxic, short-chain sphingolipid.

应用

C4 Ceramide (d18:1/4:0) has been used to study its role in rescuing and stabilizing ΔF508-cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR).

生化/生理作用

C4 Ceramide (d18:1/4:0) is implicated in a series of mutual autophosphorylation and phosphorylation actions between 3-phosphoinositide-dependent kinase 1 (PDK1) and serum/glucocorticoid-induced protein kinase 1 (SGK1). It stimulates cyclic adenosine monophosphate (cAMP)-activated chloride secretion and represses hypersecretion of interleukin-8 (IL-8). C4 Ceramide might be a potential therapeutic for cystic fibrosis (CF).

包装

5 mL Amber Glass Screw Cap Vial (860504P-5mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable